4-(6-Methoxy-2-naphthyl)-2-butanone

Basic Information

View in Editor

CAS Number

42924-53-8

Molecular Formula

C15H16O2

Molecular Weight

228.29 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

80-810C

Boiling Point

372.3°C at 760 mmHg

Flash Point

165.4 °C

Solubility

Soluble in alcohol or chloroform

Refractive Index

1.5542 (estimate)

SMILES

View in Editor

CC(=O)CCC1=CC2=C(C=C1)C=C(C=C2)OC

InChI

InChI=1S/C15H16O2/c1-11(16)3-4-12-5-6-14-10-15(17-2)8-7-13(14)9-12/h5-10H,3-4H2,1-2H3

InChIKey

BLXXJMDCKKHMKV-UHFFFAOYSA-N

LogP

3.370000000000002

Topological Polar Surface Area

26.3 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

262

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

nabumetone
Prestwick1_000909
NABUMETONE (MART.)
SR-01000759138-3
NABUMETONE (USP-RS)
Arthaxan
4-(6-Methoxy-2-naphthyl)-2-butanone
DTXCID2025472
NABUMETONE [USAN]
Nabumetonum (INN-Latin)
Spectrum4_000174
GTPL7245
NCGC00016853-02
AB00052392
DB00461
NC00579
BIDD:GT0104
KBioGR_000687
BRN 2103472
Spectrum_001486
NCGC00016853-01
BRL14777
NABUMETONE [EP MONOGRAPH]
M01AX01
NABUMETONE [ORANGE BOOK]
NABUMETONE [VANDF]
AM20040460
AB00052392_15
EN300-1853581
Relif
NABUMETONE (EP MONOGRAPH)

MDL Number

MFCD00079518

Customs Code

2914399090

FAQ

What are the physical and chemical properties of 4-(6-Methoxy-2-naphthyl)-2-butanone (CAS: 42924-53-8)?

4-(6-Methoxy-2-naphthyl)-2-butanone (CAS: 42924-53-8) is a white to off-white crystalline powder with a molecular weight of approximately 252.27 g/mol. It has a slight solubility in water and is highly soluble in organic solvents like methanol and acetone. Chemically, it is moderately reactive and can undergo various chemical transformations, including oxidation and reduction reactions.

How is 4-(6-Methoxy-2-naphthyl)-2-butanone (CAS: 42924-53-8) typically synthesized?

4-(6-Methoxy-2-naphthyl)-2-butanone (CAS: 42924-53-8) is typically synthesized via the condensation of 2-butanone with 6-methoxynaphthalene in the presence of a strong acid catalyst such as sulfuric acid. The reaction is carried out under reflux conditions, and the product is purified by recrystallization from a suitable solvent.

What industries use 4-(6-Methoxy-2-naphthyl)-2-butanone (CAS: 42924-53-8)?

4-(6-Methoxy-2-naphthyl)-2-butanone (CAS: 42924-53-8) is used in various industries, particularly in pharmaceuticals for the synthesis of certain drug intermediates, and in the production of dyes and pigments. It also has applications in the manufacturing of certain polymers and as a precursor in the development of sensor materials.

What precautions should be taken when handling 4-(6-Methoxy-2-naphthyl)-2-butanone (CAS: 42924-53-8)?

When handling 4-(6-Methoxy-2-naphthyl)-2-butanone (CAS: 42924-53-8), it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Work should be conducted in a well-ventilated area or within a fume hood. In case of a spill, immediately clean up using appropriate absorbent materials and ensure proper disposal of waste. Always refer to the Safety Data Sheet (SDS) for detailed safety information.