(2S)-2-{[(Benzyloxy)carbonyl]amino}butanoic acid

Basic Information

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CAS Number

42918-86-5

Molecular Formula

C12H15NO4

Molecular Weight

237.26 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Boiling Point

430.3℃ at 760 mmHg

SMILES

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CCC(C(=O)O)NC(=O)OCC1=CC=CC=C1

InChI

InChI=1S/C12H15NO4/c1-2-10(11(14)15)13-12(16)17-8-9-6-4-3-5-7-9/h3-7,10H,2,8H2,1H3,(H,13,16)(H,14,15)/t10-/m0/s1

InChIKey

SZQMTCSQWUYUML-JTQLQIEISA-N

LogP

1.776

Topological Polar Surface Area

75.63 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

261

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Z-L-2Abu-OH
(S)-N-alpha-BenZyloxycarbonal-2-aminobutanoic acid (CbZ-L-2Abu-OH)
(2S)-2-(phenylmethoxycarbonylamino)butanoic acid
Q-101721
Butanoic acid, 2-[[(phenylmethoxy)carbonyl]amino]-, (2S)-
(2S)-2-{[(benzyloxy)carbonyl]amino}butanoic acid
Z-Abu-OH
n-benzyloxycarbonyl-2(s)-aminobutyric acid
SCHEMBL265512
(2S)-2-[[(Phenylmethoxy)carbonyl]amino]butanoic acid
AMY25356
(S)-2-(((Benzyloxy)carbonyl)amino)butanoic acid
O10196
42918-86-5
J-300327
SZQMTCSQWUYUML-JTQLQIEISA-N
DS-12438
(S)-2-(Cbz-amino)butyric Acid
(S)-2-(BENZYLOXYCARBONYLAMINO)BUTANOIC ACID
MFCD00077006
Z-Abu(2)-OH
AKOS016842415
Benzyloxycarbonyl-L-2-aminobutyric acid
Z-D-Abu-OH
Z-2-Abu-OH
Cbz-Abu-OH
CS-W012856
M06083
EN300-117056
DTXSID401216618
(S)-2-(Benzyloxycarbonylamino)butyric acid

MDL Number

MFCD00077006

Customs Code

2924299090

FAQ

What is (2S)-2-{[(Benzyloxy)carbonyl]amino}butanoic acid (CAS: 42918-86-5)?

(2S)-2-{[(Benzyloxy)carbonyl]amino}butanoic acid, also known as N-(benzyloxycarbonyl)-leucine or Z-Leu, is an amino acid derivative with the CAS number 42918-86-5. It is a white to off-white solid with a molecular formula of C13H17NO3 and a molecular weight of 249.29 g/mol. It is used in pharmaceuticals and as a research tool in peptide synthesis.

What are the main uses of (2S)-2-{[(Benzyloxy)carbonyl]amino}butanoic acid (CAS: 42918-86-5)?

(2S)-2-{[(Benzyloxy)carbonyl]amino}butanoic acid is primarily used as a protecting group for the leucine amino acid in peptide chemistry. It is also utilized in the pharmaceutical industry for intermediate synthesis and as a research reagent in biochemistry and drug development.

Is (2S)-2-{[(Benzyloxy)carbonyl]amino}butanoic acid (CAS: 42918-86-5) safe?

(2S)-2-{[(Benzyloxy)carbonyl]amino}butanoic acid (CAS: 42918-86-5) is generally considered safe for laboratory use, but proper handling and storage should be followed. It is non-toxic, but direct contact with skin or ingestion can cause irritation. It should be handled with gloves and in a well-ventilated area. Avoid inhalation of dust and avoid contact with eyes and skin.

How should (2S)-2-{[(Benzyloxy)carbonyl]amino}butanoic acid (CAS: 42918-86-5) be stored?

(2S)-2-{[(Benzyloxy)carbonyl]amino}butanoic acid should be stored in a tightly closed container at room temperature to avoid moisture and light. It should be kept away from heat and direct sunlight. Store it in a cool, dry place and away from incompatible substances like acids and strong bases.