4-Cycloocten-1-ol

Basic Information

View in Editor

CAS Number

4277-34-3

Molecular Formula

C8H14O

Molecular Weight

126.2 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Hydrocarbons

Basic Physical Properties

Boiling Point

202.2°C at 760 mmHg

SMILES

View in Editor

OC1CCC/C=C\CC1

InChI

InChI=1S/C8H14O/c9-8-6-4-2-1-3-5-7-8/h1-2,8-9H,3-7H2

InChIKey

UCPDHOTYYDHPEN-UHFFFAOYSA-N

LogP

1.8676

Topological Polar Surface Area

20.23 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

96.7

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Cyclooct-4-enol
5-HYDROXY-1-CYCLOOCTENE
cyclooct-4-en-1-ol
(E)-cyclooct-4-enol
(Z)-5-hydroxycyclooct-1-ene
(Z)-5-Hydroxycyclooctene
(Z)-cyclooct-4-enol
4-Cycloocten-1-ol
5-hydroxycyclooctene
5-hydroxy-cyclooctene
cis-cyclooctene-5-ol
Cyclooctene-5-ol
(4Z)-cyclooct-4-en-1-ol
4-Cyclooctenol
NSC119487
1-Hydroxy-4-cyclooctene
(E)-4-Cyclooctene-1-ol
(4z)-4-cycloocten-1-ol
UCPDHOTYYDHPEN-UPHRSURJSA-N
Y5431
ST24024709

MDL Number

MFCD06252442

FAQ

What are the physical and chemical properties of 4-Cycloocten-1-ol (CAS: 4277-34-3)?

4-Cycloocten-1-ol is a colorless to pale yellow liquid with a molecular weight of approximately 128.22 g/mol. It has a specific gravity of 0.905 g/cm³ and a boiling point of 169-170°C. The compound is soluble in water (5.6 g/100 ml at 20°C) and is reactive towards acidic and basic conditions. It is also known for its use as a precursor in organic synthesis and as a fragrance ingredient.

How is 4-Cycloocten-1-ol (CAS: 4277-34-3) typically synthesized?

4-Cycloocten-1-ol is commonly synthesized via the oxidation of cyclooctene using hydrogen peroxide in the presence of a base like potassium hydroxide. The reaction is conducted in a solvent such as water or methanol at room temperature. The yield is typically around 70-80%, and the purity can be increased through recrystallization or distillation.

What industries use 4-Cycloocten-1-ol (CAS: 4277-34-3)?

4-Cycloocten-1-ol is used in various industries. It serves as a valuable intermediate in the synthesis of pharmaceuticals and natural product analogs. Additionally, it is used in the production of fragrances and perfumes due to its pleasant scent. In the polymer industry, it can be incorporated into polymer formulations to improve flexibility and solvent resistance. Furthermore, it is used in the development of sensors and semiconductors for its unique chemical properties.

What precautions should be taken when handling 4-Cycloocten-1-ol (CAS: 4277-34-3)?

When handling 4-Cycloocten-1-ol, it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. It is advised to work in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate absorbents, and the area should be flushed with water. Safe storage is crucial; the compound should be kept in a cool, dry place, away from direct sunlight and sources of ignition. A Material Safety Data Sheet (MSDS) should always be readily available for reference.