6-Bromo-N-methyl-2-naphthamide

Basic Information

View in Editor

CAS Number

426219-35-4

Molecular Formula

C12H10BrNO

Molecular Weight

264.12 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

465.8°C at 760 mmHg

SMILES

View in Editor

CNC(=O)C1=CC2=C(C=C1)C=C(C=C2)Br

InChI

InChI=1S/C12H10BrNO/c1-14-12(15)10-3-2-9-7-11(13)5-4-8(9)6-10/h2-7H,1H3,(H,14,15)

InChIKey

HPUCFMPIKISIIO-UHFFFAOYSA-N

LogP

2.961900000000001

Topological Polar Surface Area

29.1 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

244

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

SCHEMBL313250
I10169
6-bromo-N-methyl-2-naphtamide
HPUCFMPIKISIIO-UHFFFAOYSA-N
426219-35-4
DTXSID20619294
AKOS015999000
6-bromo-N-methylnaphthalene-2-carboxamide
6-bromo-N-methyl-2-naphthamide
DS-18257
CS-M1437
J-518446
6-BROMO-N-METHYL-2-NAPHTHALENECARBOXAMIDE
FT-0741184
6-Bromo-N-methyl-2-naphthamide
6-Bromo-N-Methyl-2-Naphtoamide
6-Bromo-N-methyl-2-naphthalenecarboxamide
PubChem20304
RW3090
RL03644
BC004524
6-bromo-N-methyl-naphthalene-2-carboxamide
AB0024877
ST24029686
W6234
219B354

MDL Number

MFCD14708203

FAQ

What are the physical and chemical properties of 6-Bromo-N-methyl-2-naphthamide (CAS: 426219-35-4)?

6-Bromo-N-methyl-2-naphthamide is a crystalline solid with a molecular weight of approximately 258.15 g/mol. It is slightly soluble in water but soluble in organic solvents. This compound is known for its high reactivity, particularly towards nucleophiles and reducing agents.

How is 6-Bromo-N-methyl-2-naphthamide (CAS: 426219-35-4) typically synthesized?

6-Bromo-N-methyl-2-naphthamide can be synthesized by brominating 2-naphthamide and then methylating the resulting bromo compound. This process typically involves using NBS (n-bromosuccinimide) as a brominating agent and methyl iodide for the alkylation step, with appropriate catalysts and solvents to achieve high yield and selectivity.

What industries use 6-Bromo-N-methyl-2-naphthamide (CAS: 426219-35-4)?

6-Bromo-N-methyl-2-naphthamide is primarily used in the pharmaceutical and chemical industries. It serves as a key intermediate in the synthesis of various drug compounds and also finds applications in the development of sensors and semiconductors.

What precautions should be taken when handling 6-Bromo-N-methyl-2-naphthamide (CAS: 426219-35-4)?

When handling 6-Bromo-N-methyl-2-naphthamide, appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. Work should be conducted in a well-ventilated area or fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbents and disposed of according to local regulations. Always refer to the safety data sheet (SDS) for detailed handling instructions.