(6alpha,11beta)-9-Fluoro-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione

Basic Information

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CAS Number

426-13-1

Molecular Formula

C22H29FO4

Molecular Weight

376.47 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Polymers and Plastics Thermoplastics Polyolefins

Basic Physical Properties

Melting Point

292-303°C

Boiling Point

527.1°Cat760mmHg

Flash Point

272.6°C

Refractive Index

1.574

Specific Rotation

55° (c=1, Pyridine)

SMILES

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CC1CC2C3CCC(C3(CC(C2(C4(C1=CC(=O)C=C4)C)F)O)C)(C(=O)C)O

InChI

InChI=1S/C22H29FO4/c1-12-9-17-15-6-8-21(27,13(2)24)20(15,4)11-18(26)22(17,23)19(3)7-5-14(25)10-16(12)19/h5,7,10,12,15,17-18,26-27H,6,8-9,11H2,1-4H3/t12-,15-,17-,18-,19-,20-,21-,22-/m0/s1

InChIKey

FAOZLTXFLGPHNG-KNAQIMQKSA-N

LogP

2.923300000000001

Topological Polar Surface Area

74.6 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

787

Safety Information

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Hazard Statement

Synonyms & References

English

MLS001076157
Pregna-1,20-dione, 9-fluoro-11,17-dihydroxy-6-methyl-, (6.alpha.,11.beta.)-
Delmeson
NSC-33001
SR-01000003019
component of Neo-Oxylone
D10AA01
CCG-220718
S01BA07
FLUOROMETHOLONE (USP-RS)
Fluorometholone, United States Pharmacopeia (USP) Reference Standard
FML S.O.P.
DTXCID5027435
NSC33001
FLUOROMETHOLONE (USP MONOGRAPH)
FLUOROMETHOLONE [USP MONOGRAPH]
CS-0013955
Fluorometolona (INN-Spanish)
HY-B1893
fluorometholone
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-6-methyl-, (6alpha,11beta)-
Fluorometholon
Flumetholon
C05AA06
Fluorometholone, British Pharmacopoeia (BP) Reference Standard
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-6-methyl-, (6.alpha.,11.beta.)-
Fluor-Op
BDBM50103631
FLUOROMETHOLONE [ORANGE BOOK]
BSPBio_000935
NS00007682

MDL Number

MFCD00056461

Customs Code

2937229000

FAQ

What is (6alpha,11beta)-9-Fluoro-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione (CAS: 426-13-1)?

This compound, with the CAS number 426-13-1, is a steroid derivative characterized by its fluoro and hydroxy groups. It has the chemical formula C22H32FO5 and is known for its structural complexity, making it relevant in biochemical research. It is a white crystalline solid with moderate solubility in organic solvents and is often used as a precursor in the synthesis of various bioactive compounds.

What are the main uses of (6alpha,11beta)-9-Fluoro-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione (CAS: 426-13-1)?

This compound is primarily used in pharmaceutical research for the development of steroid-based drugs. It serves as a key intermediate in the synthesis of corticosteroids and other hormone-related compounds. Additionally, it is employed in organic chemistry for structural studies and in biochemistry for understanding steroid metabolism and biological activity.

Is (6alpha,11beta)-9-Fluoro-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione (CAS: 426-13-1) safe?

The safety of (6alpha,11beta)-9-Fluoro-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione (CAS: 426-13-1) depends on its handling and application. As a chemical compound, it may exhibit potential toxicity if inhaled, ingested, or exposed to skin. Proper protective equipment, such as gloves and safety goggles, should be used when handling this substance to ensure safety in laboratory settings.

How should (6alpha,11beta)-9-Fluoro-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione (CAS: 426-13-1) be stored?

This compound should be stored in a cool, dry, and dark place to maintain stability. It is best kept in a sealed container at a temperature below 25°C and away from moisture and light. Storage in a well-ventilated area is recommended, and it should be protected from incompatible materials to prevent degradation or chemical reactions.