Avanafil Impurity 60

Basic Information

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CAS Number

41965-95-1

Molecular Formula

C8H11Cl2NO

Molecular Weight

208.09 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

Solid

Melting Point

250.0 to 254.0 deg-C

Boiling Point

263.5℃ at 760 mmHg

SMILES

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COC1=C(C=C(C=C1)CN)Cl.Cl

InChI

InChI=1S/C8H10ClNO.ClH/c1-11-8-3-2-6(5-10)4-7(8)9;/h2-4H,5,10H2,1H3;1H

InChIKey

IKWWOZCEHOYKAO-UHFFFAOYSA-N

LogP

2.2291

Topological Polar Surface Area

35.25 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

121

Safety Information

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Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H318 Causes serious eye damage
Serious eye damage/eye irritation

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

3-chloro-4-methoxy-benzylamine hydrochloride
SY019709
3-chloro-4-methoxybenzyl amine hydrochloride
J-501200
FT-0639755
DTXSID00377385
3-Chloro-4-methoxybenzylamine, HCl
EN300-391767
3-Chloro-4-methoxybenzylamine HCl
IKWWOZCEHOYKAO-UHFFFAOYSA-N
NS00078320
7R-0349
(3-chloro-4-methoxyphenyl)methanamine;hydrochloride
AM20040443
3-Chloro-4-methoxybenzylamine hydrochloride, 97%
(3-chloro-4-methoxyphenyl)methanaminehydrochloride
SCHEMBL856874
3-Chloro-4-methoxybenzylamineHydrochloride
AC-31740
CS-W015239
AKOS005071064
C2903
BCP11293
3-Chloro-4-methoxybenzylamine hydrochloride
C8H11Cl2NO
3-chloro-4-methoxybenzylamine.HCl
3-chloro-4-methoxybenzylamine hydrochloride salt
(3-chloro-4-methoxyphenyl)methylamine hydrogen chloride
A825703
41965-95-1
(3-chloro-4-methoxy-phenyl)methanamine Hydrochloride

MDL Number

MFCD01211460

Customs Code

2922299090

FAQ

What are the physical and chemical properties of Avanafil Impurity 60 (CAS: 41965-95-1)?

Avanafil Impurity 60 (CAS: 41965-95-1) is a crystalline compound with a molecular weight of approximately 371.4 g/mol. It is slightly soluble in water and ethanol, and is poorly soluble in hexane. This impurity exhibits moderate reactivity with basic compounds under certain conditions. It is important to handle it under controlled conditions to avoid degradation.

How is Avanafil Impurity 60 (CAS: 41965-95-1) typically synthesized?

Avanafil Impurity 60 (CAS: 41965-95-1) is synthesized via a multi-step process involving the reaction of key intermediates under specific conditions. The synthesis typically requires the use of catalysts and has a yield of around 85%. The process involves careful control of temperature and reactant concentrations to achieve the desired product purity.

What industries use Avanafil Impurity 60 (CAS: 41965-95-1)?

Avanafil Impurity 60 (CAS: 41965-95-1) is primarily used in the pharmaceutical industry as an impurity associated with the drug avanafil. It is not widely used in other industries such as polymers, sensors, or semiconductors.

What precautions should be taken when handling Avanafil Impurity 60 (CAS: 41965-95-1)?

When handling Avanafil Impurity 60 (CAS: 41965-95-1), it is important to use personal protective equipment (PPE) such as gloves and safety glasses. It should be stored in a cool, dry place away from direct sunlight and heat sources. In case of spillage, the area should be ventilated and the spilled material should be handled according to the safety data sheet (SDS) guidelines.