2-Amino-N-methylbenzamide

Basic Information

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CAS Number

4141-08-6

Molecular Formula

C8H10N2O

Molecular Weight

150.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

77.0 to 81.0 deg-C

Boiling Point

346.7℃ at 760 mmHg

Flash Point

163.5℃

SMILES

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CNC(=O)C1=CC=CC=C1N

InChI

InChI=1S/C8H10N2O/c1-10-8(11)6-4-2-3-5-7(6)9/h2-5H,9H2,1H3,(H,10,11)

InChIKey

KIMWOULVHFLJIU-UHFFFAOYSA-N

LogP

0.6284000000000001

Topological Polar Surface Area

55.120000000000005 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

147

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

N-Methyl 2-aminobenzamide
2-Amino-N-Methyl-Benzamide
AQ-360/40271990
A846764
N-methyl anthranilamide
CV23116700
benzamide, 2-amino-n-methyl-
CHEBI:81147
PS-4059
SB76067
Cambridge id 5107708
AM20061032
Q27155102
C17512
MFCD00060602
SCHEMBL375579
CS-W004940
Oprea1_113871
N-Methylanthranilamide
Z57124070
2-(Methylcarbamoyl)aniline
4141-08-6
DTXSID30308703
SY005082
Benzamide, o-amino-N-methyl-
NSC-207861
FT-0635148
NSC207861
2-Amino-N-methylbenzamide
NIOSH/CV2311670
2-Aminobenzoylmethylamide

MDL Number

MFCD00060602

FAQ

What are the physical and chemical properties of 2-Amino-N-methylbenzamide (CAS: 4141-08-6)?

2-Amino-N-methylbenzamide (CAS: 4141-08-6) is a crystalline solid with a molecular weight of approximately 169.19 g/mol. It is sparingly soluble in water but more soluble in organic solvents like ethanol and dimethylformamide. It is moderately reactive in basic conditions and less reactive in acidic environments. This compound is stable under normal storage conditions but should be protected from strong oxidizing agents and heat.

How is 2-Amino-N-methylbenzamide (CAS: 4141-08-6) typically synthesized?

2-Amino-N-methylbenzamide (CAS: 4141-08-6) is typically synthesized via a condensation reaction between 2-methylbenzoyl chloride and ammonia in the presence of a base like triethylamine. The reaction is carried out under mild conditions and provides a yield of up to 85%. The product is purified by recrystallization from ethanol.

What industries use 2-Amino-N-methylbenzamide (CAS: 4141-08-6)?

2-Amino-N-methylbenzamide (CAS: 4141-08-6) is used in the pharmaceutical industry as a precursor for the synthesis of various drugs. It is also utilized in the polymer industry as a stabilizing agent and in the sensor industry for its chemoresponsive properties. Additionally, it has applications in the semiconductor industry for its use in certain manufacturing processes.

What precautions should be taken when handling 2-Amino-N-methylbenzamide (CAS: 4141-08-6)?

When handling 2-Amino-N-methylbenzamide (CAS: 4141-08-6), it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. Work should be carried out in a well-ventilated area or a fume hood. In case of a spill, the area should be cleaned up with appropriate caution, and the Material Safety Data Sheet (MSDS) should be referenced for detailed spill procedures.