N-[(Benzyloxy)carbonyl]alanine

Basic Information

View in Editor

CAS Number

4132-86-9

Molecular Formula

C11H13NO4

Molecular Weight

223.23 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

112.0 to 116.0 deg-C

Boiling Point

422.1℃ at 760 mmHg

Flash Point

209.1℃

Refractive Index

1.4960 (estimate)

SMILES

View in Editor

CC(C(=O)O)NC(=O)OCC1=CC=CC=C1

InChI

InChI=1S/C11H13NO4/c1-8(10(13)14)12-11(15)16-7-9-5-3-2-4-6-9/h2-6,8H,7H2,1H3,(H,12,15)(H,13,14)

InChIKey

TYRGLVWXHJRKMT-UHFFFAOYSA-N

LogP

1.3859000000000001

Topological Polar Surface Area

75.63 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

248

Synonyms & References

English

DL-Alanine, N-[(phenylmethoxy)carbonyl]-
n-carbobenzyloxy-dl-alanine
NSC-88469
N-Benzoxycarbonyl-L-alanine
DS-13903
AM20060833
Cbz-D-Ala-OH
91280-19-2
NSC88469
N-Benzyloxycarbonyl-d,l-alanine
(2R)-2-(benzyloxycarbonylamino)propanoate
NCIOpen2_005571
carbobenzyloxy-D,L-alanine
2-{[(benzyloxy)carbonyl]amino}propanoic acid
NSC27684
4132-86-9
Carbobenzoxy-L-alanine
2-Benzyloxycarbonylamino-propionic acid
2-(((Benzyloxy)carbonyl)amino)propanoic acid
NS00125557
HY-W012381
(S)-2-(((Benzyloxy)carbonyl)amino)propanoic acid
carbobenzoxy-dl-alanine
NSC-156978
NSC-523825
N-Benzyloxycarbonyl-DL-alanine
SR-01000079047
DL-Cbz-alanine
NSC-27684
N-Carbobenzoxyalanine
CS-W013097

MDL Number

MFCD00063125

FAQ

What are the physical and chemical properties of N-[(Benzyloxy)carbonyl]alanine (CAS: 4132-86-9)?

N-[(Benzyloxy)carbonyl]alanine (CAS: 4132-86-9) is a white crystalline powder with a molecular weight of approximately 244.24 g/mol. It is slightly soluble in water but has good solubility in organic solvents. The compound shows moderate reactivity towards nucleophiles and can undergo esterification and amide formation reactions with good selectivity and yield.

How is N-[(Benzyloxy)carbonyl]alanine (CAS: 4132-86-9) typically synthesized?

N-[(Benzyloxy)carbonyl]alanine (CAS: 4132-86-9) is typically synthesized through the coupling of benzyloxycarbonyl chloride and alanine in the presence of a base such as triethylamine. The reaction involves an acylation of the amino group of alanine, leading to a high yield of the desired compound with good selectivity.

What industries use N-[(Benzyloxy)carbonyl]alanine (CAS: 4132-86-9)?

N-[(Benzyloxy)carbonyl]alanine (CAS: 4132-86-9) is used in the pharmaceutical industry for the synthesis of peptides and proteins. It is also utilized in the polymer industry for the creation of functionalized polymers. Additionally, it can be applied in sensor and semiconductor technology for specific applications requiring amino acid functionalities.

What precautions should be taken when handling N-[(Benzyloxy)carbonyl]alanine (CAS: 4132-86-9)?

When handling N-[(Benzyloxy)carbonyl]alanine (CAS: 4132-86-9), appropriate personal protective equipment (PPE) should be worn, including gloves and safety goggles. The compound should be stored in a cool, dry place away from direct sunlight and heat sources. In the event of a spill, it should be immediately contained and properly disposed of according to the safety data sheet (SDS). Handling should be done in a well-ventilated area or under a fume hood.