Memantine hydrochloride

Basic Information

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CAS Number

41100-52-1

Molecular Formula

C12H22ClN

Molecular Weight

215.77 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

Physical State

Powder

Melting Point

292°C

Boiling Point

239.8 °C at 760 mmHg

Density

0.8030

Flash Point

92.3 °C

SMILES

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CC12CC3CC(C1)(CC(C3)(C2)N)C.Cl

InChI

InChI=1S/C12H21N.ClH/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10;/h9H,3-8,13H2,1-2H3;1H

InChIKey

LDDHMLJTFXJGPI-UHFFFAOYSA-N

LogP

3.115900000000001

Topological Polar Surface Area

26.02 Å²

Hydrogen Bond Donor/Acceptor

2 / 1

Complexity

240

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

SW060653-4
CHEBI:64323
3,5-Dimethyl-1-adamantanamine hydrochloride
DTXSID90961439
MEMANTINE HYDROCHLORIDE [JAN]
3,5-dimethyladamantan-1-amine hy-drochloride
Acrescent
BCP9000253
SY057917
EU-0100861
NCGC00094186-02
N06DX01
Mantine
MEMANTINE HYDROCHLORIDE (USP MONOGRAPH)
MEMANTINE HYDROCHLORIDE [MART.]
Akatinol
SUN Y7017
SR-01000075458
NMI-131
MEMANTINE HYDROCHLORIDE [WHO-DD]
NCGC00261546-01
M 9292
(3,5-Dimethyl-1-adamantyl)amine hydrochloride
Memantine Mylan
Memantine hydrochloride (JAN/USP)
FT-0650723
Balaxur
NSC102290
MEMANTINE HYDROCHLORIDE [USP-RS]
NamendaXR
Q27133218

MDL Number

MFCD00214336

Customs Code

2921300090

FAQ

What is Memantine hydrochloride (CAS: 41100-52-1)?

Memantine hydrochloride (CAS: 41100-52-1) is a medication used to treat moderate to severe Alzheimer's disease. It is a derivative of memantine, an NMDA receptor antagonist, with the chemical formula C10H17N3O·HCl. It appears as a white crystalline powder, is soluble in water, and has a molecular weight of approximately 229.7 g/mol. Its primary role is to regulate glutamate activity in the brain, which helps slow the progression of Alzheimer's symptoms.

What are the main uses of Memantine hydrochloride (CAS: 41100-52-1)?

Memantine hydrochloride (CAS: 41100-52-1) is primarily used as a treatment for moderate to severe Alzheimer's disease. It is also employed in research to study NMDA receptor function and may be used in veterinary medicine for similar neurological conditions. Its applications are focused on managing cognitive decline and as a pharmaceutical compound in clinical trials for neurodegenerative disorders.

Is Memantine hydrochloride (CAS: 41100-52-1) safe?

Memantine hydrochloride (CAS: 41100-52-1) is generally safe when used as prescribed, with common side effects including dizziness, confusion, and headache. It is approved by the FDA for Alzheimer's treatment and follows strict safety guidelines. Proper handling, such as avoiding skin and eye contact, and storage in a secure location are essential to ensure safety during use and handling.

How should Memantine hydrochloride (CAS: 41100-52-1) be stored?

Memantine hydrochloride (CAS: 41100-52-1) should be stored in a cool, dry place, away from direct light, in a tightly sealed container. It is stable at temperatures between 20-25°C and should be protected from moisture. Proper storage conditions are critical to maintaining its efficacy and preventing degradation over time.