Methyl 4-acetamido-2-methoxybenzoate

Basic Information

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CAS Number

4093-29-2

Molecular Formula

C11H13NO4

Molecular Weight

223.23 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

128.0 to 132.0 deg-C

Boiling Point

417.5℃ at 760 mmHg

Density

1.2±0.1 g/cm3

Flash Point

206.3±25.9 °C

Refractive Index

1.552

SMILES

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CC(=O)NC1=CC(=C(C=C1)C(=O)OC)OC

InChI

InChI=1S/C11H13NO4/c1-7(13)12-8-4-5-9(11(14)16-3)10(6-8)15-2/h4-6H,1-3H3,(H,12,13)

InChIKey

OERVVBDWGVOBIS-UHFFFAOYSA-N

LogP

1.4402

Topological Polar Surface Area

64.63 Å²

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

267

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

methyl 4-(acetylamino)-2-methoxybenzoate
Methyl 4-acetamido-2-methoxybenzoate
M2776
NS00030877
Methyl 4-acetamido-o-anisate
methyl-4-acetamido-2-methoxybenzoate
CAS-4093-29-2
METOCLOPRAMIDE IMPURITY D [EP IMPURITY]
CHEMBL3560107
W-106330
Benzoic acid, 4-(acetylamino)-2-methoxy-, methyl ester
EINECS 223-839-6
4-acetamido-2-methoxybenzoic acid methyl ester
OERVVBDWGVOBIS-UHFFFAOYSA-N
AKOS003238555
Methyl 4-(acetylamino)-o-anisate
FT-0635121
DS-17905
Q27292298
MetocloprDmide EP Impurity D
SCHEMBL2555975
4-Acetamido-o-anisic Acid Methyl Ester
NCGC00262910-01
SB79893
DTXSID7057739
SR-01000945021
MFCD00065258
W4UJW899BA
4-Acetylamino-2-methoxy-benzoic acid methyl ester
4093-29-2
SY034819

MDL Number

MFCD00065258

Customs Code

2942000000

FAQ

What are the physical and chemical properties of Methyl 4-acetamido-2-methoxybenzoate (CAS: 4093-29-2)?

Methyl 4-acetamido-2-methoxybenzoate is a white crystalline solid with a molecular weight of approximately 274.36 g/mol. It has good solubility in organic solvents like methanol and acetone but is insoluble in water. It is relatively stable under normal conditions but can react with strong acids to form the corresponding carboxylic acid. This compound is used in the synthesis of pharmaceuticals and other chemical intermediates.

How is Methyl 4-acetamido-2-methoxybenzoate (CAS: 4093-29-2) typically synthesized?

Methyl 4-acetamido-2-methoxybenzoate is typically synthesized by esterification of 4-acetamido-2-methoxybenzoic acid with methanol in the presence of an acid catalyst such as sulfuric acid. The reaction yields a high purity product with good selectivity and yield. The process involves heating the reaction mixture under reflux conditions for several hours.

What industries use Methyl 4-acetamido-2-methoxybenzoate (CAS: 4093-29-2)?

Methyl 4-acetamido-2-methoxybenzoate is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It is also utilized in the production of some polymers and in the development of sensors and semiconductors due to its chemical reactivity and stability.

What precautions should be taken when handling Methyl 4-acetamido-2-methoxybenzoate (CAS: 4093-29-2)?

When handling Methyl 4-acetamido-2-methoxybenzoate, it is important to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be handled by sweeping or vacuuming up, then disposing of the material according to local waste regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and safety information.