4-Fluorobenzenesulfonamide

Basic Information

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CAS Number

402-46-0

Molecular Formula

C6H6FNO2S

Molecular Weight

175.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

124-127 °C

Boiling Point

307.9℃/760mmHg

Density

1.428

Water Solubility

It is soluble in water.

Flash Point

140°C

Refractive Index

1.554

SMILES

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C1=CC(=CC=C1F)S(=O)(=O)N

InChI

InChI=1S/C6H6FNO2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,(H2,8,9,10)

InChIKey

LFLSATHZMYYIAQ-UHFFFAOYSA-N

LogP

0.4731000000000003

Topological Polar Surface Area

60.160000000000004 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

213

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

MFCD00025384
EN300-01202
Q27092928
A825003
4-Fluorobenzenesulfonamide, 98%
Benzenesulfonamide, 4-fluoro-
4-fluorobenzene-1-sulfonamide
SCHEMBL283919
Z45415567
CS-0072364
LFLSATHZMYYIAQ-UHFFFAOYSA-N
4-11-00-00102 (Beilstein Handbook Reference)
Benzenesulfonamide, p-fluoro-
W-106372
p-Fluorobenzenesulphonamide
p-Fluorobenzenesulfonamide
4-Fluorobenzenesulfonamide
4-fluoro-benzenesulfonamide
DTXSID70193195
Cambridge id 5135296
FT-0601463
F0953
O11230
PS-8602
AKOS000122248
PD008429
A825005
4-FLOUROBENZENESULFONAMIDE
UWB1PR3UR6
4-fluorobenzene sulfonamide
BRN 2832246

MDL Number

MFCD00025384

Customs Code

2935009090

FAQ

What regulatory guidelines apply to 4-Fluorobenzenesulfonamide (CAS: 402-46-0)?

4-Fluorobenzenesulfonamide (CAS: 402-46-0) is subject to various regulatory guidelines. It must comply with the GHS (Global Harmonized System of Classification and Labelling of Chemicals) for hazard communication. In Europe, it falls under the REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) regulation. The FDA and EPA in the United States also have specific requirements for the handling and use of this compound. Manufacturers and importers must ensure compliance with these regulations to ensure safety and environmental protection.

Are there alternatives to 4-Fluorobenzenesulfonamide (CAS: 402-46-0) in synthesis?

Several alternatives to 4-Fluorobenzenesulfonamide (CAS: 402-46-0) are available in synthesis. Common alternatives include other sulfonamides with different substituents, such as 4-Chlorobenzenesulfonamide, or other fluoroaromatic compounds like 4-Fluorobenzenesulfonic acid. Researchers often explore these options to achieve similar functional groups or chemical properties while potentially offering better reactivity or fewer environmental concerns.

What is the market or research trend for 4-Fluorobenzenesulfonamide (CAS: 402-46-0)?

The market for 4-Fluorobenzenesulfonamide (CAS: 402-46-0) is steadily growing due to its utility in pharmaceutical and chemical synthesis. Research trends focus on its application in organic synthesis, particularly in the development of new drugs and materials. The trend also involves exploring its environmental impact and developing more sustainable synthesis methods. As regulatory requirements evolve, there is a growing emphasis on green chemistry practices to reduce the environmental footprint of this compound.

How should waste containing 4-Fluorobenzenesulfonamide (CAS: 402-46-0) be handled?

Waste containing 4-Fluorobenzenesulfonamide (CAS: 402-46-0) should be managed safely to avoid environmental contamination. It is advisable to collect the waste in appropriate containers and store them in a well-ventilated area. For disposal, contact a professional waste management service specializing in hazardous chemicals. Incineration can be an effective method, but it must be conducted in an industrial incinerator with proper emissions control. Always follow local regulations and guidance from environmental authorities to ensure safe disposal.