Acebutolol EP Impurity C

Basic Information

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CAS Number

40188-45-2

Molecular Formula

C12H15NO3

Molecular Weight

221.26 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

120-126 °C

Boiling Point

428 ℃ at 760 mmHg

Density

1.2±0.1 g/cm3

Flash Point

212.6±25.9 °C

Refractive Index

1.579

SMILES

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CCCC(=O)NC1=CC(=C(C=C1)O)C(=O)C

InChI

InChI=1S/C12H15NO3/c1-3-4-12(16)13-9-5-6-11(15)10(7-9)8(2)14/h5-7,15H,3-4H2,1-2H3,(H,13,16)

InChIKey

FGWZEOPEZISTTR-UHFFFAOYSA-N

LogP

2.3334000000000006

Topological Polar Surface Area

66.4 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

265

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

NS00005024
SR-01000058746-1
Ac-HoPhe-OH
SR-01000058746
N-(3-acetyl-4-hydroxyphenyl)-bu-tanamide
ACEBUTOLOL HYDROCHLORIDE IMPURITY C [EP IMPURITY]
AMY37078
EINECS 254-831-0
FT-0639620
Butanamide, N-(3-acetyl-4-hydroxyphenyl)-
A824966
CAS-40188-45-2
3'-Acetyl-4'-hydroxybutyranilide
DTXCID8031526
14QJB65R4V
CHEMBL3184751
2-Acetyl-4-Butyramidephenol
W-106380
N-(3-Acetyl-4-hydroxyphenyl)butanamide
MFCD00798556
N-(3-Acetyl-4-hydroxyphenyl)butanamide, 97%
PD065550
FGWZEOPEZISTTR-UHFFFAOYSA-N
NCGC00253700-01
CS-0204647
N-(3-Acetyl-4-hydroxyphenyl)butyramide
EC 254-831-0
Acebutolol impurity C, European Pharmacopoeia (EP) Reference Standard
Z56347249
2-Acetyl-4-butyramidophenol
AC-15462

MDL Number

MFCD00798556

Customs Code

2924299090

FAQ

What is Acebutolol EP Impurity C (CAS: 40188-45-2)?

Acebutolol EP Impurity C is a chemical compound with CAS number 40188-45-2, a byproduct of the synthesis of acebutolol. It is an off-white to pale yellow powder with a molecular weight of approximately 418.49. This impurity is characterized by its bitter taste and poor solubility in water.

What are the main uses of Acebutolol EP Impurity C (CAS: 40188-45-2)?

Acebutolol EP Impurity C is primarily used in pharmaceutical research as a reference material for impurity testing and quality control in the development of acebutolol and related beta-blocker drugs. It is not used in clinical applications due to its impurity status.

Is Acebutolol EP Impurity C (CAS: 40188-45-2) safe?

Acebutolol EP Impurity C is generally considered safe for laboratory use under controlled conditions. However, it should be handled with care, and appropriate personal protective equipment (PPE) should be worn. Exposure to this impurity should be minimized, and spills should be cleaned up promptly following safety guidelines.

How should Acebutolol EP Impurity C (CAS: 40188-45-2) be stored?

Acebutolol EP Impurity C should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly sealed container to prevent moisture absorption. Optimal storage conditions are between 15°C and 25°C (59°F and 77°F), with relative humidity below 60%. The container should be protected from physical damage and kept out of reach of children and unauthorized persons.