5-Nitro-8-quinolinol

Basic Information

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CAS Number

4008-48-4

Molecular Formula

C9H6N2O3

Molecular Weight

190.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

181-183 °C

Boiling Point

419°C at 760 mmHg

Flash Point

419 °C at 760mmHg

Solubility

alcohol: very slightly soluble

Refractive Index

1.5570 (estimate)

SMILES

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C1=CC2=C(C=CC(=C2N=C1)O)[N+](=O)[O-]

InChI

InChI=1S/C9H6N2O3/c12-8-4-3-7(11(13)14)6-2-1-5-10-9(6)8/h1-5,12H

InChIKey

RJIWZDNTCBHXAL-UHFFFAOYSA-N

LogP

1.99

Complexity

229

Safety Information

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GHS Hazard Pictograms

H301

H311

H315

H319

H331

H335

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H311 Toxic in contact with skin
Acute toxicity, dermal

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H331 Toxic if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 6.1 Class 6.1

Sensitiveness

对空气敏感，对光线敏感

Synonyms & References

English

W-106391
CHEBI:67121
UNII-A8M33244M6
Nitroxolina
Pharmakon1600-01506173
DTXCID2026284
5-Nitro-quinolin-8-ol
Noxin
DB01422
NITROXOLINE [MART.]
Opera_ID_204
5-Nitroquinolin-8-ol, 96%
Nitroxolina [INN-Spanish]
SCHEMBL151248
Noxibiol
CAS-4008-48-4
BDBM64987
KUC105356N
NSC 74947
Nitroxolinum
Nitroxolin
NITROXOLINE [INN]
8-Hydroxy-5-nitroquinoline
Galinok
8-Quinolinol, 5-nitro-
8-Hydroxy-5-nitro-chinoline
EN300-17364
DTXSID4046284
Nicene Forte
Tox21_111969
KSC-8-140

MDL Number

MFCD00006791

Customs Code

2933499090

FAQ

What is 5-Nitro-8-quinolinol (CAS: 4008-48-4)?

5-Nitro-8-quinolinol is an organic compound with the chemical formula C9H7N3O3. It features a quinoline ring substituted with a nitro group at position 5 and a hydroxyl group at position 8. This compound is commonly used as an intermediate in pharmaceutical and chemical synthesis due to its versatile functional groups and reactivity. Its molecular structure contributes to its applications in drug development and industrial processes.

What are the main uses of 5-Nitro-8-quinolinol (CAS: 4008-48-4)?

5-Nitro-8-quinolinol is primarily used in pharmaceuticals as a precursor for antifungal and antibiotic compounds. It also finds applications in industrial chemistry for dye production and as a component in certain pesticides. In research settings, it serves as a building block for synthesizing complex molecules. Additionally, it is utilized in the development of organic materials and as an analytical reagent in chemical studies.

Is 5-Nitro-8-quinolinol (CAS: 4008-48-4) safe?

5-Nitro-8-quinolinol is considered hazardous due to potential skin and eye irritation. It should be handled with appropriate protective equipment, such as gloves and safety goggles, and in a well-ventilated area. Safety standards recommend following OSHA guidelines and proper disposal protocols. While it is not classified as carcinogenic, its handling requires caution to ensure workplace safety.

How should 5-Nitro-8-quinolinol (CAS: 4008-48-4) be stored?

5-Nitro-8-quinolinol should be stored in a cool, dry, and light-protected environment. It is best kept in a sealed container to prevent moisture absorption and degradation. Storage conditions should maintain a temperature between 2-8°C to ensure stability. Avoid exposure to air and incompatible substances to maintain its chemical integrity over time.