1-Methoxy-2-(trifluoromethyl)benzene

Basic Information

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CAS Number

395-48-2

Molecular Formula

C8H7F3O

Molecular Weight

176.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

SMILES

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COC1=CC=CC=C1C(F)(F)F

InChI

InChI=1S/C8H7F3O/c1-12-7-5-3-2-4-6(7)8(9,10)11/h2-5H,1H3

InChIKey

BHPJMWUXVOTGQU-UHFFFAOYSA-N

LogP

2.7140000000000004

Topological Polar Surface Area

9.23 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

144

Safety Information

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Hazard Statement

Synonyms & References

English

2-(Trifluoromethyl)anisole
2-trifluoromethyl anisole
QWAMWTWEVCYDEL-UHFFFAOYSA-N
PS-8588
FT-0612825
A824612
Benzene,1-(1,1-dimethylethoxy)-2-(trifluoromethyl)-
CS-0194670
SCHEMBL255270
E89410
2-methoxybenzotrifluoride
MFCD00142938
A810353
AKOS005257892
trifluoromethylanisole
1-(1,1-dimethylethoxy)-2-(trifluoromethyl)-benzene
395-48-2
1-methoxy-2-(trifluoromethyl)benzene
1-Methoxy-2-(trifluoromethyl)benzene
1-Methoxy-2-trifluoromethylbenzene
2-METHOXYBENZOTRIFLUORIDE
Anisole,o-(trifluoromethyl)- (5CI)
o-(Trifluoromethyl)anisole

MDL Number

MFCD00142938

FAQ

What regulatory guidelines apply to 1-Methoxy-2-(trifluoromethyl)benzene (CAS: 395-48-2)?

1-Methoxy-2-(trifluoromethyl)benzene (CAS: 395-48-2) is regulated under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) and follows specific criteria for classification as a hazardous chemical. In the European Union, it is subject to the REACH regulations, which require pre-market assessment of the health and environmental impacts. It is also controlled under the EPA and FDA for safe handling, storage, and disposal, especially due to its potential toxicity and flammability.

Are there alternatives to 1-Methoxy-2-(trifluoromethyl)benzene in synthesis (CAS: 395-48-2)?

While 1-Methoxy-2-(trifluoromethyl)benzene (CAS: 395-48-2) is a valuable intermediate in organic synthesis, alternatives include other anisole derivatives like 2-methoxy-1-(trifluoromethyl)benzene and its isomers. Common substitutes include 2-chloro-1-(trifluoromethyl)benzene and 2-fluoro-1-(trifluoromethyl)benzene, which can serve similar functions in some reactions due to their structural similarities.

What is the market or research trend for 1-Methoxy-2-(trifluoromethyl)benzene (CAS: 395-48-2)?

The research trend for 1-Methoxy-2-(trifluoromethyl)benzene (CAS: 395-48-2) is aligned with the increasing demand for fluorinated compounds in pharmaceuticals and agrochemicals due to their enhanced bioavailability and stability. Market trends show a steady increase in demand, driven by innovations in synthesis and the development of new applications. Research is focusing on improving synthetic methods for better yield and selectivity.

How should waste containing 1-Methoxy-2-(trifluoromethyl)benzene (CAS: 395-48-2) be handled?

Waste containing 1-Methoxy-2-(trifluoromethyl)benzene (CAS: 395-48-2) should be collected in secure containers and properly labeled. It should be disposed of through professional waste disposal services that comply with local regulations. Incineration is a common method for disposing of this waste, but it must be done in a controlled environment to minimize environmental impact. Precautions should include ensuring proper ventilation and the use of protective equipment to prevent exposure to the compound.