Compound Q&A

Are there alternatives to 1-Methoxy-2-(trifluoromethyl)benzene in synthesis (CAS: 395-48-2)?

Answer

1-Methoxy-2-(trifluoromethyl)benzene
While 1-Methoxy-2-(trifluoromethyl)benzene (CAS: 395-48-2) is a valuable intermediate in organic synthesis, alternatives include other anisole derivatives like 2-methoxy-1-(trifluoromethyl)benzene and its isomers. Common substitutes include 2-chloro-1-(trifluoromethyl)benzene and 2-fluoro-1-(trifluoromethyl)benzene, which can serve similar functions in some reactions due to their structural similarities.

About

CAS No 395-48-2
English Name 1-Methoxy-2-(trifluoromethyl)benzene
Molecular Formula C8H7F3O
Molecular Weight 176.14 g/mol
SMILES COC1=CC=CC=C1C(F)(F)F
InChIKey BHPJMWUXVOTGQU-UHFFFAOYSA-N
Last Updated: 2026-03-05 21:52

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