Boceprevir | CAS No. 394730-60-0

Boceprevir

Basic Information

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CAS Number

394730-60-0

Molecular Formula

C27H45N5O5

Molecular Weight

519.69 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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CC(C)(C)NC(=O)N[C@H](C(=O)N1C[C@H]2[C@@H]([C@H]1C(=O)NC(CC3CCC3)C(=O)C(=O)N)C2(C)C)C(C)(C)C

InChI

InChI=1S/C27H45N5O5/c1-25(2,3)20(30-24(37)31-26(4,5)6)23(36)32-13-15-17(27(15,7)8)18(32)22(35)29-16(19(33)21(28)34)12-14-10-9-11-14/h14-18,20H,9-13H2,1-8H3,(H2,28,34)(H,29,35)(H2,30,31,37)/t15-,16?,17-,18-,20+/m0/s1

InChIKey

LHHCSNFAOIFYRV-DOVBMPENSA-N

LogP

1.7112000000000023

Topological Polar Surface Area

150.70000000000002 Å²

Hydrogen Bond Donor/Acceptor

5 / 10

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

boceprevir
[14C]-Boceprevir
BOCEPRAVIR
BOCEPREVIR EBP520 SCH503034
Boceprevir metabolites SCH 534128
Boceprevir SCH 534129 (Inactive metabolite)
EBP 520
EBP-520
SCH 503034
SCH-503034
(1R,2S,5S)-N-(4-Amino-1-cyclobutyl-3,4-dioxobutan-2-yl)-3-[(2S)-2-(tert-butylcarbamoylamino)-3,3-dimethylbutanoyl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide
Boceprevir

MDL Number

MFCD22208555

FAQ

What is Boceprevir (CAS: 394730-60-0)?

Boceprevir (CAS: 394730-60-0) is a direct-acting antiviral medication used in the treatment of chronic hepatitis C. It is a protease inhibitor that specifically targets the NS3/4A protease of the hepatitis C virus, thereby inhibiting viral replication. Boceprevir is administered in combination with other antiviral drugs to improve the effectiveness of treatment.

What are the main uses of Boceprevir (CAS: 394730-60-0)?

Boceprevir (CAS: 394730-60-0) is primarily used for the treatment of chronic hepatitis C, especially for patients with genotype 1 infection. It is often used in combination with pegylated interferon and ribavirin to enhance the antiviral efficacy and improve the cure rate of the disease.

Is Boceprevir (CAS: 394730-60-0) safe?

Boceprevir (CAS: 394730-60-0) is generally considered safe when used under the guidance of a healthcare professional. However, it can cause side effects such as anemia, diarrhea, and fatigue. Patients should be monitored closely for any adverse reactions. Care should be taken to avoid interactions with other medications and to follow prescribed dosing instructions.

How should Boceprevir (CAS: 394730-60-0) be stored?

Boceprevir (CAS: 394730-60-0) should be stored at room temperature (15-30°C) away from direct sunlight and moisture. The medication should be kept in a tightly closed container to protect it from light. It is important to store it in a place that is accessible only to authorized individuals to prevent accidental exposure.