2,6-Dichloro-4-fluorophenol

Basic Information

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CAS Number

392-71-2

Molecular Formula

C6H3Cl2FO

Molecular Weight

180.99 g/mol

Chemical Classification

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

48.0 to 51.0 deg-C

Boiling Point

142 °C

Flash Point

218 °F

Refractive Index

1.567

SMILES

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C1=C(C=C(C(=C1Cl)O)Cl)F

InChI

InChI=1S/C6H3Cl2FO/c7-4-1-3(9)2-5(8)6(4)10/h1-2,10H

InChIKey

BOJVIFKSTRCIRJ-UHFFFAOYSA-N

LogP

2.8380999999999994

Topological Polar Surface Area

20.23 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

110

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class 8 Class 8

Synonyms & References

English

2,3-dichloro-6-fluoro-phenol
A824504
3-(2-THIENYLTHIO)BUTANOICACID
PS-10215
2,6-Dichloro-4-fluorophenol
CS-0190996
D2204
SCHEMBL374815
Phenol, 2,6-dichloro-4-fluoro-
392-71-2
NSC10257
NSC-10257
FT-0610580
DTXSID30192447
MFCD00010675
NS00120468
AKOS015849935
NSC 10257
2,6-Dichloro-4-fluorophenol, 98%
2,6-dichloro-4-fluoro-phenol
4-Fluoro-2,6-dichlorophenol
InChI=1/C6H3Cl2FO/c7-4-1-3(9)2-5(8)6(4)10/h1-2,10H
BOJVIFKSTRCIRJ-UHFFFAOYSA-
2,6-Dichlor-4-fluor-phenol
4-Fluor-2.6-dichlor-1-hydroxy-benzol
4-fluoro-2,6-dichlorophenol
C6H3Cl2FO
PubChem2871
Phenol,2,6-dichloro-4-fluoro-
SBB089743
CM11717

MDL Number

MFCD00010675

Customs Code

2908199090

FAQ

What are the physical and chemical properties of 2,6-Dichloro-4-fluorophenol (CAS: 392-71-2)?

2,6-Dichloro-4-fluorophenol is a white or pale yellow crystalline solid with a molecular weight of approximately 212.01 g/mol. It has a solubility of about 0.06 g/100 mL in water and is more soluble in organic solvents. The compound is relatively stable but can react with bases to form phenoxide salts. It is also known to react with reducing agents and is used in the synthesis of other compounds.

How is 2,6-Dichloro-4-fluorophenol (CAS: 392-71-2) typically synthesized?

2,6-Dichloro-4-fluorophenol is typically synthesized by the reaction of 4-fluoroaniline with chlorine gas in the presence of a Lewis acid catalyst, such as aluminum chloride. The process involves chlorination at both the 2 and 6 positions on the phenyl ring, followed by purification steps to isolate the desired product with high selectivity and yield.

What industries use 2,6-Dichloro-4-fluorophenol (CAS: 392-71-2)?

2,6-Dichloro-4-fluorophenol is used in various industries, including the pharmaceutical industry for the synthesis of certain drugs, the polymer industry for the production of various polymer-based products, and the chemical industry for the development of sensors and other chemical intermediates.

What precautions should be taken when handling 2,6-Dichloro-4-fluorophenol (CAS: 392-71-2)?

When handling 2,6-Dichloro-4-fluorophenol, it is essential to use personal protective equipment (PPE) such as gloves, goggles, and lab coats. It should be stored in a fume hood and handled in a well-ventilated area to avoid inhalation of vapors. In case of a spill, it should be handled according to the Material Safety Data Sheet (MSDS) and appropriate safety measures should be taken. Exposure to this compound may cause skin irritation and respiratory issues, so it is crucial to follow all safety guidelines.