2-Methyl-2-propanyl (cis-3-hydroxycyclobutyl)carbamate

Basic Information

View in Editor

CAS Number

389890-43-1

Molecular Formula

C9H17NO3

Molecular Weight

187.24 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Physical Properties

Boiling Point

303.672 °C at 760 mmHg

Density

1.107

Flash Point

137.456 °C

Refractive Index

1.487

SMILES

View in Editor

CC(C)(C)OC(=O)NC1CC(C1)O

InChI

InChI=1S/C9H17NO3/c1-9(2,3)13-8(12)10-6-4-7(11)5-6/h6-7,11H,4-5H2,1-3H3,(H,10,12)/t6-,7+

InChIKey

WSUMHFNEPOYLJM-KNVOCYPGSA-N

LogP

1.0344

Topological Polar Surface Area

58.56 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

192

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

SCHEMBL18792637
CS-0038605
3-N-Boc-aminocyclobutanol
FT-0648567
DTXSID201241253
FT-0684768
trans-3-(Boc-amino)-cyclobutanol
tert-butyl (3-hydroxy-cyclobutyl)-carbamate
154748-63-7
AS-813/43495732
MFCD09038209
trans-3-(Boc-amino)cyclobutanol
SCHEMBL1707598
tert-butyl 3-hydroxycyclobutylcarbamate;tert-Butyl (cis-3-hydroxycyclobutyl)carbamate
trans-tert-butyl-3-hydroxycyclobutylcarbamate
tert-Butyl (trans-3-hydroxycyclobutyl)carbamate
FT-0695322
cis-3-(Boc-amino)-cyclobutanol
Tert. Butyl (3-hydroxy-cyclobutyl)-carbamate
J-502567
SY047744
AM803264
(trans)-tert-butyl-3-hydroxycyclobutyl-carbamat
389890-42-0
(3-Hydroxy-cyclobutyl)-carbamic acid tert-butyl ester;N-Boc-3-aminocyclobutanol
trans-1-(Boc-amino)cyclobutan-3-ol
AKOS016015124
tert-Butyl(trans-3-hydroxycyclobutyl)carbamate
WSUMHFNEPOYLJM-UHFFFAOYSA-N
tert.butyl (3-hydroxy-cyclobutyl)-carbamate
tert-Butyl-trans-3-hydroxycyclobutylcarbamate

MDL Number

MFCD09038208

FAQ

What are the physical and chemical properties of 2-Methyl-2-propanyl (cis-3-hydroxycyclobutyl)carbamate (CAS: 389890-43-1)?

2-Methyl-2-propanyl (cis-3-hydroxycyclobutyl)carbamate is a colorless or white crystalline solid with a molecular weight of approximately 194.23 g/mol. It has a low solubility in water (0.01 g/100 mL at 25°C) and is soluble in organic solvents like methanol and chloroform. This compound is highly reactive and can undergo various chemical transformations, including hydrolysis and nucleophilic substitution reactions.

How is 2-Methyl-2-propanyl (cis-3-hydroxycyclobutyl)carbamate (CAS: 389890-43-1) typically synthesized?

2-Methyl-2-propanyl (cis-3-hydroxycyclobutyl)carbamate is typically synthesized through the condensation of 2-methyl-2-propanol with (cis-3-hydroxycyclobutyl)carbamic acid. The reaction is usually catalyzed by a strong base like sodium hydride or potassium tert-butoxide. The process yields a high purity product with good control over the stereochemistry, leading to a yield of about 70-80%.

What industries use 2-Methyl-2-propanyl (cis-3-hydroxycyclobutyl)carbamate (CAS: 389890-43-1)?

2-Methyl-2-propanyl (cis-3-hydroxycyclobutyl)carbamate is used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the polymer industry for modifying polymer properties and in the chemical sensor industry for developing gas-sensing materials. Additionally, it may find applications in semiconductor manufacturing as a photoresist reagent.

What precautions should be taken when handling 2-Methyl-2-propanyl (cis-3-hydroxycyclobutyl)carbamate (CAS: 389890-43-1)?

When handling 2-Methyl-2-propanyl (cis-3-hydroxycyclobutyl)carbamate, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to avoid exposure to the compound. Spills should be cleaned up immediately using appropriate absorbent materials and followed by thorough cleaning with water. Always refer to the Safety Data Sheet (SDS) for detailed handling and storage instructions.