Amlodipine Impurity 6 (N-(2-Hydroxyethyl)phthalimide)

Basic Information

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CAS Number

3891-07-4

Molecular Formula

C10H9NO3

Molecular Weight

191.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Physical State

Crystalline Powder

Melting Point

128.0 to 131.0 deg-C

Boiling Point

356.5℃ at 760 mmHg

Flash Point

169.4±23.2 °C

Solubility

DMSO (Slightly), Methanol (Slightly)

Refractive Index

1.622

Vapor Pressure

0.0±0.8 mmHg at 25°C

SMILES

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C1=CC=C2C(=C1)C(=O)N(C2=O)CCO

InChI

InChI=1S/C10H9NO3/c12-6-5-11-9(13)7-3-1-2-4-8(7)10(11)14/h1-4,12H,5-6H2

InChIKey

MWFLUYFYHANMCM-UHFFFAOYSA-N

LogP

0.27490000000000014

Topological Polar Surface Area

57.61 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

240

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

N-Hydroxyethylphthalimide
2-Phthalimidoethanol
Phthalimide, N-2-hydroxyethyl-
N-[2-hydroxyethyl]phthalimide
SY048556
2-(2-Hydroxyethyl)-1H-isoindole-1,3(2H)-dione
2-Hydroxyethylphthalimide
NSC2773
CS-W021382
MWFLUYFYHANMCM-UHFFFAOYSA-
EN300-18323
FT-0676029
AC-29753
N-(2-Hydroxyethyl)phthalimide
N-(2-hydroxyethyl)-phthalimide
61842K53O1
2-(2-HYDROXYETHYL)-2,3-DIHYDRO-1H-ISOINDOLE-1,3-DIONE
2-(2-hydroxyethyl) isoindole-1,3-dione
H0245
1H-Isoindole-1,3(2H)-dione, 2-(2-hydroxyethyl)-
MFCD00005903
NSC-50624
3891-07-4
2-(2-hydroxyethyl)isoindole-1,3-dione
N-(2-hydroxyethyl)-phtalimide
Phthalimide, N-(2-hydroxyethyl)-
NSC50624
EINECS 223-434-4
N-2-Hydroxyethyl phthalimide
NSC-2773
UNII-61842K53O1

MDL Number

MFCD00005903

Customs Code

2925190090

FAQ

What is Amlodipine Impurity 6 (CAS: 3891-07-4)?

Amlodipine Impurity 6, also known as N-(2-Hydroxyethyl)phthalimide (CAS: 3891-07-4), is a chemical compound used in pharmaceutical research. It has the molecular formula C10H12N2O3 and is typically a white crystalline solid. The compound is characterized by its phthalimide ring structure and hydroxyethyl substituent, making it relevant for drug impurity analysis and quality control.

What are the main uses of Amlodipine Impurity 6 (CAS: 3891-07-4)?

Amlodipine Impurity 6 is primarily used in pharmaceutical quality control to identify and quantify impurities in Amlodipine drug substances. It also serves as a research reagent in organic synthesis and analytical chemistry. Its applications include testing for purity, stability studies, and regulatory compliance in drug development processes.

Is Amlodipine Impurity 6 (CAS: 3891-07-4) safe?

Amlodipine Impurity 6 is not intended for direct human use and requires careful handling. While it is a byproduct of pharmaceutical synthesis, safety protocols include wearing protective gloves, goggles, and lab coats. Proper disposal is essential, and it should be stored in accordance with hazardous material regulations to ensure laboratory safety and environmental compliance.

How should Amlodipine Impurity 6 (CAS: 3891-07-4) be stored?

Amlodipine Impurity 6 should be stored in a cool, dry place, away from light and moisture. Maintain storage conditions at 2-8°C (refrigerated) to ensure stability. Use airtight, sealed containers made of glass or HDPE to prevent contamination. Avoid exposure to air and heat to maintain the compound's integrity and prolong shelf life.