Carbidopa Monohydrate

Basic Information

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CAS Number

38821-49-7

Molecular Formula

C10H14N2O4

Molecular Weight

226.23 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Physical State

Not available

Melting Point

211-215°C

Boiling Point

Not available

Density

Not available

Flash Point

Not available

Solubility

Aqueous Acid (Slightly), DMSO (Slightly)

Vapor Pressure

Not available

Specific Rotation

-14 ~ -18° (c=0.3, MeOH)

SMILES

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NNC(C(=O)O)(Cc1ccc(c(c1)O)O)C

InChI

InChI=1S/C10H14N2O4/c1-10(12-11,9(15)16)5-6-2-3-7(13)8(14)4-6/h2-4,12-14H,5,11H2,1H3,(H,15,16)

InChIKey

TZFNLOMSOLWIDK-UHFFFAOYSA-N

LogP

-0.053100000000000036

Topological Polar Surface Area

115.81 Å²

Hydrogen Bond Donor/Acceptor

6 / 6

Complexity

261

Safety Information

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GHS Hazard Pictograms

H319

Hazard Statement

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

Carbidopa
(+)-2-(3,4-Dihydroxybenzyl)-2-hydrazinopropionic acid monohydrate
Carbidopa Monohydrate
(S)-Carbidopa
S-(−)-Carbidopa
S-(-)-Carbidopa
(S)-(-)-CARBIDOPA MONOHYDRATE
(S)-3-(3,4-Dihydroxyphenyl)-2-hydrazino-2-methylpropionic acid monohydrate
0.4
CARBIDOPA 1-HYDRATE
CARBIDOPA 1-HYDRATE,PHARMA
CARBIDOPA HYDRATE
CARBIDOPA(GMP CERTIFICATE)
CARBIDOPA,USP
Hydroxyethyl starch 130
lodosyn
(S)-(-)-carbidopa
N-Aminomethyldopa
alpha-Methyldopahydrazine
Carbidopum
Carbidopa anhydrous
L-alpha-Methyldopahydrazine
Carbidopum [INN-Latin]
Carbidopa (anhydrous)
Hadrazino-alpha-methyldopa
Lodosin
C-DOPA
L-3-(3,4-Dihydroxyphenyl)-2-methyl-2-hydrazinopropionic acid
(-)-L-alpha-Hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic acid
S(-)-CARBIDOPA
(2S)-3-(3,4-dihydroxyphenyl)-2-hydrazin

MDL Number

MFCD00889211

Customs Code

2932999099

FAQ

What regulatory guidelines apply to Carbidopa Monohydrate (CAS: 38821-49-7)?

Carbidopa Monohydrate (CAS: 38821-49-7) is subject to regulatory guidelines under the Globally Harmonized System (GHS) for classification and labeling, as well as REACH regulations in the European Union. In the United States, the FDA and EPA have specific requirements for the handling, storage, and transportation of this compound due to its use in pharmaceuticals and its potential environmental impact.

Are there alternatives to Carbidopa Monohydrate (CAS: 38821-49-7) in synthesis?

In synthesis, alternatives to Carbidopa Monohydrate (CAS: 38821-49-7) include using its parent compound, Carbidopa, or exploring other dopa derivatives. However, Carbidopa Monohydrate is often preferred due to its stability and effectiveness. Common alternatives for synthesis might include 3,4-dihydroxyphenylalanine (L-DOPA) or its derivatives, which can serve as starting materials for this compound.

What is the market or research trend for Carbidopa Monohydrate (CAS: 38821-49-7)?

The market for Carbidopa Monohydrate (CAS: 38821-49-7) shows steady growth driven by the increasing prevalence of Parkinson's disease and related conditions. Research trends are focusing on its potential in combination therapies and exploring its mechanisms to enhance its efficacy and reduce side effects. Additionally, there is ongoing interest in understanding its pharmacokinetics and developing more stable forms for improved patient compliance.

How should waste containing Carbidopa Monohydrate (CAS: 38821-49-7) be handled?

Waste containing Carbidopa Monohydrate (CAS: 38821-49-7) should be collected in appropriate containers and stored in a secure, well-ventilated area. It should be disposed of through a professional waste disposal service that complies with local regulations. Environmental protection precautions include monitoring for leaks and ensuring proper incineration or chemical treatment to prevent contamination. Always follow local and international environmental protection guidelines.