4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole

Basic Information

View in Editor

CAS Number

388116-27-6

Molecular Formula

C14H18BNO2

Molecular Weight

243.12 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

168-173 °C

Boiling Point

396°C at 760 mmHg

Density

1.11

Flash Point

193.3℃

Refractive Index

1.562

SMILES

View in Editor

B1(OC(C(O1)(C)C)(C)C)C2=C3C=CNC3=CC=C2

InChI

InChI=1S/C14H18BNO2/c1-13(2)14(3,4)18-15(17-13)11-6-5-7-12-10(11)8-9-16-12/h5-9,16H,1-4H3

InChIKey

QDCIXBBEUHMLDN-UHFFFAOYSA-N

LogP

2.4671000000000003

Topological Polar Surface Area

34.25 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

316

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

SY012840
J-513434
4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl) 1H-indole
RB2036
4-(4,4,5,5-tetramethyl[1,3,2]-dioxaborolan-2-yl)-1H-indole
4-(4,4,5,5-tetramethyl(1,3,2]dioxaborolan-2-yl)-1H-indole
388116-27-6
4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole
DTXSID20462343
1H-Indole-4-boronic acid, pinacol ester
Indol-4-boronic acid pinacol ester
MFCD08689896
FT-0684797
4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole
4-(4,4,5,5-tetra-methyl-[1,3,2]dioxaborolan-2-yl)-1H-indole
A824286
4-(4,4,5 ,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-indole
(1H-INDOL-4-YL)BORONIC ACID PINACOL ESTER
AM20040345
Indole-4-boronic acid pinacol ester
QDCIXBBEUHMLDN-UHFFFAOYSA-N
Indole-4-boronic acid pinacol ester, 95%
4-(4,4,5,5tetramethyl[1,3,2]-dioxaborolan-2-yl)-1H-indole
4-(4,4,5,5,-tetramethyl-[1,3,2]dioxaborolane-2-yl)-1H-indole
4-indole boronic acid pinacol ester
CS-W019752
EN300-6480642
4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-indole
Z2037316489
SCHEMBL476853
PB34318

MDL Number

MFCD08689896

Customs Code

2933990090

FAQ

What regulatory guidelines apply to 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole (CAS: 388116-27-6)?

The compound 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole (CAS: 388116-27-6) is regulated under various guidelines including the Globally Harmonized System (GHS) for classification and labeling of chemicals, the Registration, Evaluation, Authorization, and Restriction of Chemicals (REACH) in the EU, and the Toxic Substances Control Act (TSCA) in the US. FDA and EPA may also have specific requirements depending on its intended use.

Are there alternatives to 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole (CAS: 388116-27-6) in synthesis?

There are several alternatives to 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole (CAS: 388116-27-6) in synthesis, such as using other boronic acids or esters. Common alternatives include 2-bromobenzeneboronic acid, 2-fluorobenzeneboronic acid, or 2-halo-1,3,2-dioxaborinanes, which can serve similar roles in cross-coupling reactions.

What is the market or research trend for 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole (CAS: 388116-27-6)?

The market for 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole (CAS: 388116-27-6) is growing due to its application in medicinal chemistry and materials science. Research trends include its use as a key intermediate in organic synthesis and its potential in developing new drugs and materials. The demand is expected to rise with ongoing advancements in synthetic chemistry and pharmaceutical research.

How should waste containing 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole (CAS: 388116-27-6) be handled?

Waste containing 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole (CAS: 388116-27-6) should be collected in an appropriate container and stored in a well-ventilated area away from ignition sources. It should be disposed of through a professional waste disposal service that complies with local regulations. Environmental protection measures include ensuring no spills occur and that the waste is handled in a manner that minimizes environmental impact.