1,1,1,3,3,3-Hexafluoro-2-propanol

Basic Information

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CAS Number

38701-74-5

Molecular Formula

C3H2F6O

Molecular Weight

170.05 g/mol

Chemical Classification

Fine Chemicals Specialty Chemicals UV Stabilizers

Electronic Chemicals Semiconductor Materials Etchants

Water Treatment Chemicals Disinfectants Chlorine Compounds

Basic Physical Properties

Melting Point

−4 °C

Boiling Point

59 °C

Water Solubility

Fully miscible in water.

Flash Point

59°C

Refractive Index

n20/D 1.275(lit.)

SMILES

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C(C(F)(F)F)(C(F)(F)F)O

InChI

InChI=1S/C3H2F6O/c4-2(5,6)1(10)3(7,8)9/h1,10H

InChIKey

BYEAHWXPCBROCE-UHFFFAOYSA-N

LogP

1.4719

Topological Polar Surface Area

20.23 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

97.1

Safety Information

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GHS Hazard Pictograms

H302

H312

H314

H332

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H312 Harmful in contact with skin
Acute toxicity, dermal

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

Hazard Class

Class 8 Class 8

Sensitiveness

Moisture Sensitive

Synonyms & References

English

Deuterated 1,1,1,3,3,3-hexafluoro-2-propanol
2-deuterio-2-deuteriooxy-1,1,1,3,3,3-hexafluoropropane
1,1,1,3,3,3-Hexafluoroisopropanol-d2
BYEAHWXPCBROCE-AWPANEGFSA-N
1,1,1,3,3,3-Hexafluoro-2-propanol-d2 (HFIP-d2)
1,1,1,3,3,3-Hexafluoro(2-2H)propan-2-(2H)ol
hexafluoro(?H)propan-2-(?H)ol
1,1,1,3,3,3-Hexafluoro-2-propanol-d2
AKOS015903013
Deuterated HFP
1,1,1,3,3,3-Hexafluoro-2-propanol-d2, 99 atom % D
MFCD00037559
E79361
EINECS 254-091-9
SCHEMBL1414813
DTXSID30191995
38701-74-5
1,1,1,3,3,3-hexafluoro[2-2H]propan-2-[2H]ol
1,1,1,3,3,3-HEXAFLUORO-2-PROPANOL, [D2]
1,1,1,3,3,3-HEXAFLUOROISOPROPANOL-D2
Deuterated 1,1,1,3,3,3-hexafluoro-2-propanol,Deuterated HFP,HFP-d2
HFIP-d2
HFP-d2
Hexafluoroisopropanol-d2

MDL Number

MFCD00037559

FAQ

What regulatory guidelines apply to 1,1,1,3,3,3-Hexafluoro-2-propanol (CAS: 38701-74-5)?

1,1,1,3,3,3-Hexafluoro-2-propanol (CAS: 38701-74-5) is regulated under the Globally Harmonized System of Classification and Labeling of Chemicals (GHS) as a flammable liquid and a carcinogen. In the European Union, it falls under the REACH regulation, requiring registration and safety data sheets. The U.S. FDA may have specific guidelines for its use in pharmaceuticals, and the EPA regulates its environmental impact, handling, and disposal.

Are there alternatives to 1,1,1,3,3,3-Hexafluoro-2-propanol (CAS: 38701-74-5) in synthesis?

Alternatives to 1,1,1,3,3,3-Hexafluoro-2-propanol (CAS: 38701-74-5) include other fluorinated solvents such as 1,1,1,2,3,3,3-heptafluoropropane and perfluoropropanol. In some applications, less reactive fluorinated alcohols or non-fluorinated solvents like ethyl acetate can serve as alternatives. The choice depends on the specific reaction conditions and desired properties.

What is the market or research trend for 1,1,1,3,3,3-Hexafluoro-2-propanol (CAS: 38701-74-5)?

Research on 1,1,1,3,3,3-Hexafluoro-2-propanol (CAS: 38701-74-5) is focused on its use in pharmaceuticals and as a solvent in chemical synthesis. Market trends show increasing demand due to its unique physical properties, but there is also growing interest in finding more environmentally friendly alternatives. The trend is towards safer and more sustainable chemicals.

How should waste containing 1,1,1,3,3,3-Hexafluoro-2-propanol (CAS: 38701-74-5) be handled?

Waste containing 1,1,1,3,3,3-Hexafluoro-2-propanol (CAS: 38701-74-5) should be collected in appropriate containers, labeled as hazardous, and disposed of through professional waste disposal services. Incineration is a common method, but it must be done in an enclosed and controlled incinerator to prevent emission of fluorides. Environmental precautions include ensuring no leaks and proper ventilation during handling and disposal to minimize exposure and environmental impact.