Erythromycin Lactobionate

Basic Information

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CAS Number

3847-29-8

Molecular Formula

C49H89NO25

Molecular Weight

1060.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

145-150°C

Refractive Index

1.5300 (estimate)

SMILES

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CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)O)(C)O.C(C1C(C(C(C(O1)OC(C(CO)O)C(C(C(=O)O)O)O)O)O)O)O

InChI

InChI=1S/C36H63NO12.C12H22O12/c1-13-26-36(9,43)31(40)21(5)28(38)18(2)14-15-25(47-34-29(39)24(37(10)11)16-19(3)45-34)20(4)30(22(6)33(42)48-26)49-27-17-35(8,44-12)32(41)23(7)46-27;13-1-3(15)10(7(18)8(19)11(21)22)24-12-9(20)6(17)5(16)4(2-14)23-12/h18-27,29-32,34,39-41,43H,13-14,16-17H2,1-12H3;3-10,12-20H,1-2H2,(H,21,22)/t18-,19-,20-,21+,22-,23+,24+,25+,26-,27+,29-,30+,31-,32+,34+,35-,36-;3-,4-,5+,6+,7-,8-,9-,10-,12+/m11/s1

InChIKey

YXXKEZBSEDYUNG-RZSKHZPISA-N

LogP

-3.5530099999999996

Topological Polar Surface Area

391.2800000000001 Å²

Hydrogen Bond Donor/Acceptor

13 / 25

Complexity

1580

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Sterile erythromycin lactobionate
ERYTHROMYCIN LACTOBIONATE [WHO-IP]
ERYTHROMYCIN LACTOBIONATE [MART.]
DTXCID401436149
Q27256272
Erythromycin, 4-O-beta-D-Galactopyranosyl-D-gluconate (1:1)
ERYTHROMYCIN LACTOBIONATE [MI]
3847-29-8
CHEMBL1200506
ERYTHROMYCIN LACTOBIONATE [USP IMPURITY]
1334-39-0
erythromycin lactobionate
ERYTHROMYCIN, LACTOBIONATE (1:1) (SALT)
ERYTHROMYCIN LACTOBIONATE (MART.)
ERYTHROMYCIN MONO(4-O-.BETA.-D-GALACTOPYRANOSYL-D-GLUCONATE) (SALT)
SCHEMBL41566
Erythrocin Lactobionate
33H58I7GLQ
Erythromycin lactobionate (1:1) (salt)
ERYTHROMYCINI LACTOBIONAS [WHO-IP LATIN]
DTXSID801009322
STERILE ERYTHROMYCIN LACTOBIONATE [USP MONOGRAPH]
ERYTHROMYCIN LACTOBIONATE [ORANGE BOOK]
HY-B0220A
Erythromycini lactobionas
NS00093445
CS-0009646
EINECS 223-348-7
STERILE ERYTHROMYCIN LACTOBIONATE (USP MONOGRAPH)
D02009
Erythromycin mono(4-O-beta-D-galactopyranosyl-D-gluconate) (salt)

MDL Number

MFCD01716346

FAQ

What are the physical and chemical properties of Erythromycin Lactobionate (CAS: 3847-29-8)?

Erythromycin Lactobionate is a semi-synthetic macrolide antibiotic. It has a crystalline form and a molecular weight of approximately 1144.44 g/mol. This compound is poorly soluble in water but soluble in dilute acid. It reacts with certain reagents like acids and bases, making it prone to degradation under harsh conditions.

How is Erythromycin Lactobionate (CAS: 3847-29-8) typically synthesized?

Erythromycin Lactobionate is typically synthesized by reacting Erythromycin with calcium lactate. Commonly used catalysts include acetic acid and calcium acetate. The synthesis involves a multistep process with high yield and selectivity, leading to the formation of the desired lactobionate ester.

What industries use Erythromycin Lactobionate (CAS: 3847-29-8)?

Erythromycin Lactobionate is primarily used in the pharmaceutical industry for its antibiotic properties. It is also utilized in veterinary medicine and as a feed additive. In some specialized applications, it can be used as a sensor material in certain analytical devices.

What precautions should be taken when handling Erythromycin Lactobionate (CAS: 3847-29-8)?

When handling Erythromycin Lactobionate, it is essential to use proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work under a chemical fume hood to avoid inhalation. Spills should be cleaned up immediately using appropriate absorbents. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.