Bimatoprost acid methyl ester

Basic Information

View in Editor

CAS Number

38315-47-8

Molecular Formula

C24H34O5

Molecular Weight

402.53 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Boiling Point

557.2°C at 760 mmHg

Density

1.17

Flash Point

184°C

Refractive Index

1.59

SMILES

View in Editor

COC(=O)CCCC=CCC1C(CC(C1C=CC(CCC2=CC=CC=C2)O)O)O

InChI

InChI=1S/C24H34O5/c1-29-24(28)12-8-3-2-7-11-20-21(23(27)17-22(20)26)16-15-19(25)14-13-18-9-5-4-6-10-18/h2,4-7,9-10,15-16,19-23,25-27H,3,8,11-14,17H2,1H3/b7-2-,16-15+/t19-,20+,21+,22-,23+/m0/s1

InChIKey

UQBYFURYGYNQLQ-FDBOBMRISA-N

LogP

3.183800000000003

Topological Polar Surface Area

86.99000000000001 Å²

Hydrogen Bond Donor/Acceptor

3 / 5

Complexity

523

Synonyms & References

English

(z)-7-[(1r,2r,3r,5s)-3,5-dihydroxy-2-((e)-(s)-3-hydroxy-5-phenyl-pent-1-enyl)-cyclopentyl]-hept-5-enoic acid methyl ester
Bimatoprost Acid Methyl Ester
17-phenyl trinor Prostaglandin F2α methyl ester
(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-((S)-(E)-3-hydroxy-5-phenylpent-1-enyl)-cyclopentyl]hept-5-enoic acid methyl ester
(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-((S)-3-hydroxy-5-phenyl-pent-1-enyl)-cyclopentyl]-hept-5-enoic acid methylester
methyl ester of bimatoprost acid
9UHL27LCT4
(Z)-7-[(1R,2R,3R,5S)-3,5-DIHYDROXY-2-((E)-(S)-3-HYDROXY-5-PHENYL-PENT-1-ENYL)-CYCLOPENTYL]-HEPT-5-ENOIC ACID METHYL ESTER
Bimatoprost acid methyl ester
UNII-9UHL27LCT4
SCHEMBL4400156
17-Phenyl-18,19,20-trinor-PGF2I+/- methyl ester
17-PHENYL-18,19,20-TRINOR-PGF2.ALPHA. METHYL ESTER
Bimatoprost methyl ester
5-Heptenoic acid, 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl)cyclopentyl)-, methyl ester, (5Z)-
(5Z)-methyl 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-5-phenylpent-1-enyl)cyclopentyl)hept-5-enoate
Bimatoprost impurity D
Bimatoprost Acid Methyl Ester; 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-, methyl ester, (5Z)-; 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-pentenyl]cyclopentyl]-, methyl ester, (5Z)- (
HY-B0191B
38315-47-8
17-Phenyl-18,19,20-trinor-pgf2alpha methyl ester
methyl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]hept-5-enoate
(Z)-Methyl 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-5-phenylpent-1-en-1-yl)cyclopentyl)hept-5-enoate
(Z)-Methyl7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-5-phenylpent-1-en-1-yl)cyclopentyl)hept-5-enoate
AKOS015967183
CS-0590283
UQBYFURYGYNQLQ-FDBOBMRISA-N
(5Z)-methyl7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-5-phenylpent-1-enyl)cyclopentyl)hept-5-enoate
Q27273242
PD019601
DTXSID401255490

MDL Number

MFCD09033307

FAQ

What are the physical and chemical properties of Bimatoprost acid methyl ester (CAS: 38315-47-8)?

Bimatoprost acid methyl ester (CAS: 38315-47-8) is a white to off-white crystalline solid with a molecular weight of approximately 314.34 g/mol. It has a melting point of 82-84°C. It is slightly soluble in water but more soluble in organic solvents such as methanol and ethanol. The compound is relatively stable under normal storage conditions but should be protected from light and heat to maintain its integrity.

How is Bimatoprost acid methyl ester (CAS: 38315-47-8) typically synthesized?

Bimatoprost acid methyl ester (CAS: 38315-47-8) is typically synthesized by the methylation of bimatoprost acid. The reaction involves the use of methyl iodide in the presence of an acid catalyst such as aluminum chloride. The synthesis is carried out under anhydrous conditions to ensure high yield and selectivity, with the final product purified by recrystallization to achieve high purity.

What industries use Bimatoprost acid methyl ester (CAS: 38315-47-8)?

Bimatoprost acid methyl ester (CAS: 38315-47-8) is primarily used in the pharmaceutical industry, particularly in ophthalmic applications. It is a key intermediate in the production of bimatoprost, a drug used to treat glaucoma and ocular hypertension. While it has applications in other industries, its main use is in the healthcare sector.

What precautions should be taken when handling Bimatoprost acid methyl ester (CAS: 38315-47-8)?

When handling Bimatoprost acid methyl ester (CAS: 38315-47-8), it is important to use appropriate personal protective equipment (PPE) such as gloves and safety goggles. Store the compound in a cool, dry place away from direct sunlight and heat sources. In the event of a spill, use absorbent materials and ensure proper disposal according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.