N-(Trifluoroacetyl)glycine

Basic Information

View in Editor

CAS Number

383-70-0

Molecular Formula

C4H4F3NO3

Molecular Weight

171.07 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Specialty Chemicals UV Stabilizers

Electronic Chemicals Semiconductor Materials Etchants

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

117-121 °C

Boiling Point

291.6 ºC

Flash Point

130 ºC

SMILES

View in Editor

C(C(=O)O)NC(=O)C(F)(F)F

InChI

InChI=1S/C4H4F3NO3/c5-4(6,7)3(11)8-1-2(9)10/h1H2,(H,8,11)(H,9,10)

InChIKey

IFAXXCBMQJNCCF-UHFFFAOYSA-N

LogP

-0.2505000000000001

Topological Polar Surface Area

66.4 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

176

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

[(Trifluoroacetyl)amino]acetic acid
AB01486
AKOS001425494
(2,2,2-Trifluoro-acetylamino)-acetic acid
SY101937
2-[(2,2,2-trifluoroacetyl)amino]acetic acid
NSC-306126
A873854
TFA-GLY-OH
Glycine, N-(trifluoroacetyl)-
Z235363061
FD21629
CHEBI:145713
AMY39853
FT-0632070
N-alpha-Trifluoroacetyl-glycin (TFA-Gly-OH)
MFCD00029784
N-Trifluoroacetylglycine
383-70-0
TRIFLUOROACETYL GLYCINE
Trifluoroacetylglycine;N-(Trifluoroacetyl)glycine
NSC306126
N-Trifluoroacetyl glycine
[(Trifluoroacetyl)amino]acetic acid #
(2,2,2-TRIFLUOROACETAMIDO)ACETIC ACID
(2,2,2-Trifluoroacetyl)glycine
DTXSID30191672
AS-15586
2-(TRIFLUOROACETAMIDO)ACETIC ACID
EN300-28959
2-(2,2,2-Trifluoroacetamido)acetic acid

MDL Number

MFCD00029784

Customs Code

2924199090

FAQ

What is N-(Trifluoroacetyl)glycine (CAS: 383-70-0)?

N-(Trifluoroacetyl)glycine (CAS: 383-70-0) is an organic compound with the molecular formula C4H3F3NO2. It is a derivative of glycine with a trifluoroacetyl group attached to the amino group. This compound is colorless or white crystalline solid with a high melting point and low volatility.

What are the main uses of N-(Trifluoroacetyl)glycine (CAS: 383-70-0)?

N-(Trifluoroacetyl)glycine (CAS: 383-70-0) is primarily used in pharmaceutical research and development as a chiral auxiliary in organic synthesis. It is also used in the synthesis of peptides and as a building block in medicinal chemistry.

Is N-(Trifluoroacetyl)glycine (CAS: 383-70-0) safe?

N-(Trifluoroacetyl)glycine (CAS: 383-70-0) is considered safe for laboratory use when handled with appropriate precautions. However, it should be stored in a cool, dry place, away from incompatible materials, and never ingested or inhaled. Protective gloves and eyewear should be worn during handling.

How should N-(Trifluoroacetyl)glycine (CAS: 383-70-0) be stored?

N-(Trifluoroacetyl)glycine (CAS: 383-70-0) should be stored in a tightly closed container at a cool, dry place, away from direct sunlight and heat sources. The storage temperature should be below 30°C (86°F) to minimize degradation. It should be kept away from incompatible materials such as strong acids, bases, and oxidizers.