1-(2,4-Dimethyl-1,3-thiazol-5-yl)ethanone

Basic Information

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CAS Number

38205-60-6

Molecular Formula

C7H9NOS

Molecular Weight

155.22 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Boiling Point

230°C

Refractive Index

n20/D 1.543(lit.)

SMILES

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CC(=O)c1sc(C)nc1C

InChI

InChI=1S/C7H9NOS/c1-4-7(5(2)9)10-6(3)8-4/h1-3H3

InChIKey

BLQOKWQUTLNKON-UHFFFAOYSA-N

LogP

1.9625400000000002

Topological Polar Surface Area

29.96 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

149

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

1-(2,4-Dimethylthiazol-5-yl)ethanone
5-Acetyl-2,4-dimethylthiazole
1-(2,4-Dimethyl-1,3-thiazol-5-yl)ethanone
2,4-Dimethyl-5-acetylthiazole
5-Acetyl-2,4-dimethyl thiazole
1-(2,4-dimethyl-1,3-thiazol-5-yl)ethan-1-one

MDL Number

MFCD00005331

Customs Code

2934100090

FAQ

What are the physical and chemical properties of 1-(2,4-Dimethyl-1,3-thiazol-5-yl)ethanone (CAS: 38205-60-6)?

1-(2,4-Dimethyl-1,3-thiazol-5-yl)ethanone is a crystalline compound with a molecular weight of approximately 198.25 g/mol. It has a melting point of 91-93°C and is slightly soluble in water. Chemically, it exhibits moderate reactivity and is prone to nucleophilic substitution reactions.

How is 1-(2,4-Dimethyl-1,3-thiazol-5-yl)ethanone (CAS: 38205-60-6) typically synthesized?

1-(2,4-Dimethyl-1,3-thiazol-5-yl)ethanone is commonly synthesized via the condensation of 2,4-dimethylthiazole-5-carbaldehyde with ethylene glycol. The reaction typically requires a Lewis acid catalyst and proceeds with good yield and selectivity.

What industries use 1-(2,4-Dimethyl-1,3-thiazol-5-yl)ethanone (CAS: 38205-60-6)?

1-(2,4-Dimethyl-1,3-thiazol-5-yl)ethanone finds applications in the pharmaceutical industry for the synthesis of various drugs. It is also used in the polymer industry as a stabilizer and in the sensor industry for detecting specific chemical species.

What precautions should be taken when handling 1-(2,4-Dimethyl-1,3-thiazol-5-yl)ethanone (CAS: 38205-60-6)?

When handling 1-(2,4-Dimethyl-1,3-thiazol-5-yl)ethanone, it is essential to use personal protective equipment (PPE) such as gloves and safety glasses. Store it in a cool, dry place, away from direct sunlight. In case of spill, use appropriate absorbents and consult the Safety Data Sheet (SDS) for further instructions.