N,N'-bis(2,6-Dimethylphenyl)-1,4-piperazinediacetamide | CAS No. 380204-72-8

N,N'-bis(2,6-Dimethylphenyl)-1,4-piperazinediacetamide

Basic Information

CAS Number

380204-72-8

Molecular Formula

C24H32N4O2

Molecular Weight

408.55 g/mol

AD

Basic Physical Properties

CC1=C(C(=CC=C1)C)NC(=O)CN2CCN(CC2)CC(=O)NC3=C(C=CC=C3C)C

InChI

InChI=1S/C24H32N4O2/c1-17-7-5-8-18(2)23(17)25-21(29)15-27-11-13-28(14-12-27)16-22(30)26-24-19(3)9-6-10-20(24)4/h5-10H,11-16H2,1-4H3,(H,25,29)(H,26,30)

InChIKey

FRRCDIZIDLHOOV-UHFFFAOYSA-N

LogP

3.1150800000000016

Topological Polar Surface Area

64.68 Ų

Hydrogen Bond Donor/Acceptor

2 / 6

Complexity

506

Synonyms & References

English

  • N,N'-bis(2,6-Dimethylphenyl)-1,4-piperazinediacetamide
  • 2,2′-(Piperazine-1,4-diyl)bis[N-(2,6-dimethylphenyl)acetamide]
  • N1,N4-Bis(2,6-dimethylphenyl)-1,4-piperazinediacetamide
  • 2,2'-(piperazine-1,4-diyl)bis(N-(2,6-dimethylphenyl)acetamide)
  • 2,2'-(Piperazine-1,4-diyl)bis[N-(2,6-dimethylphenyl)acetamide]; Ranolazine Related Compound D
  • 2-[4-[2-(2,6-dimethylanilino)-2-oxoethyl]piperazin-1-yl]-N-(2,6-dimethylphenyl)acetamide
  • UNII-UGD35FKE8G
  • N-(2,6-dimethylphenyl)-2-(4-{[(2,6-dimethylphenyl)carbamoyl]methyl}piperazin-1-yl)acetamide
  • AKOS001020283
  • 380204-72-8
  • MLS000536517
  • UGD35FKE8G
  • SCHEMBL2327539
  • 1,4-Piperazinediacetamide, N,N'-bis(2,6-dimethylphenyl)-
  • Cambridge id 6514443
  • DB-326831
  • Z46189376
  • 2-(4-(2-(2,6-Dimethylanilino)-2-oxoethyl)piperazin-1-yl)-N-(2,6-dimethylphenyl)acetamide
  • Ranolazine Related Compound D
  • SMR000151386
  • S-(Trichlorovinyl)-L-cysteine
  • 1,4-Piperazinediacetamide, N1,N4-bis(2,6-dimethylphenyl)-
  • EN300-18169965
  • 2,2'-(Piperazine-1,4-diyl)bis(N-(2,6-dimethylphenyl)acetamide)

MDL Number

MFCD00347727

FAQ

What regulatory guidelines apply to N,N'-bis(2,6-Dimethylphenyl)-1,4-piperazinediacetamide (CAS: 380204-72-8)?

N,N'-bis(2,6-Dimethylphenyl)-1,4-piperazinediacetamide (CAS: 380204-72-8) falls under the scope of the REACH regulations in the European Union, which requires registration for substances above 1 ton per year. It is also classified under the Globally Harmonized System (GHS) as a harmful substance. In the United States, it is regulated by the EPA and FDA for industrial and pharmaceutical applications respectively. Compliance with safety data sheets (SDS) and material safety data sheets (MSDS) is mandatory to ensure proper handling and storage.

Are there alternatives to N,N'-bis(2,6-Dimethylphenyl)-1,4-piperazinediacetamide (CAS: 380204-72-8) in synthesis?

There are several alternatives to N,N'-bis(2,6-Dimethylphenyl)-1,4-piperazinediacetamide, including piperazine derivatives and other diamides. Isomers and analogs such as N,N'-bis(3-methylphenyl)-1,4-piperazinediacetamide can be considered as viable alternatives. For synthesis, chemists often explore isosteres and related compounds to achieve similar functionalities with potentially better reactivity or stability.

What is the market or research trend for N,N'-bis(2,6-Dimethylphenyl)-1,4-piperazinediacetamide (CAS: 380204-72-8)?

The market for N,N'-bis(2,6-Dimethylphenyl)-1,4-piperazinediacetamide is growing due to its applications in pharmaceuticals and polymer synthesis. Current research trends focus on its use as an intermediate in the development of novel pharmaceuticals and as a modifier in polymer chemistry. The increasing demand is driven by its unique chemical properties and potential in drug discovery and material science.

How should waste containing N,N'-bis(2,6-Dimethylphenyl)-1,4-piperazinediacetamide (CAS: 380204-72-8) be handled?

Waste containing N,N'-bis(2,6-Dimethylphenyl)-1,4-piperazinediacetamide (CAS: 380204-72-8) should be collected and disposed of in accordance with local and international regulations. Proper incineration or professional waste disposal services are recommended. Environmental protection measures include ensuring no spillage during handling and providing proper personal protective equipment (PPE) to avoid exposure. Compliance with SDS and MSDS guidelines is crucial for safe disposal and environmental safety.

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