6-Hydroxy-3-pyridazinecarboxylic acid

Basic Information

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CAS Number

37972-69-3

Molecular Formula

C5H4N2O3

Molecular Weight

140.1 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

246 °C

Boiling Point

518.5°C at 760 mmHg

Density

1.63

Flash Point

267.4℃

SMILES

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C1=CC(=O)NN=C1C(=O)O

InChI

InChI=1S/C5H4N2O3/c8-4-2-1-3(5(9)10)6-7-4/h1-2H,(H,7,8)(H,9,10)

InChIKey

GIFSROMQVPUQFK-UHFFFAOYSA-N

LogP

-0.11960000000000015

Topological Polar Surface Area

83.31 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

241

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

6-hydroxypyridazine-3-carboxylic acid
3-Hydroxypyridazine-6-carboxylic acid
BCP33723
6-Carboxy-3(2H)-pyridazinone
AKOS000261935
DS-0480
6-oxo-1H-pyridazine-3-carboxylic acid
6-Oxo-1,6-dihydro-3-pyridazinecarboxylic acid #
MFCD09064936
SCHEMBL287290
6-oxo-1,6-dihydropyridazine-3-carboxylic acid
6-Hydroxy-3-pyridazinecarboxylic acid
Z56878668
BB 0237015
FG-0444
CHEMBL1213607
NSC203175
PB20339
6-Oxo-1,6-dihydro-pyridazine-3-carboxylic acid
AKOS005256423
6-carboxy-3(2H)-pyridazone
NSC-203175
FT-0647091
3(2h)-pyridazinone-6-carboxylic acid
DTXSID70308343
MFCD00052805
CS-W005425
F1967-0968
6-Oxo-1,6-dihydro-pyridazine-3-carboxylic acid
37972-69-3
J-518798

MDL Number

MFCD09064936

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 6-Hydroxy-3-pyridazinecarboxylic acid (CAS: 37972-69-3)?

6-Hydroxy-3-pyridazinecarboxylic acid (CAS: 37972-69-3) is a white crystalline solid with a molecular weight of approximately 167.14 g/mol. It has a solubility of about 20 mg/mL in water and is slightly soluble in ethanol. Chemically, it is moderately reactive, showing some acidity and can form complexes with metal ions. It is stable under normal conditions but should be stored away from strong oxidizing agents and heat.

How is 6-Hydroxy-3-pyridazinecarboxylic acid (CAS: 37972-69-3) typically synthesized?

6-Hydroxy-3-pyridazinecarboxylic acid is typically synthesized via the condensation reaction of 3-pyridazinecarboxylic acid and hydroxylamine hydrochloride. This process often requires a catalyst such as sodium hydroxide or potassium hydroxide. The yield can be up to 85%, and the product can be purified by recrystallization from water or ethanol.

What industries use 6-Hydroxy-3-pyridazinecarboxylic acid (CAS: 37972-69-3)?

6-Hydroxy-3-pyridazinecarboxylic acid (CAS: 37972-69-3) is used in the pharmaceutical industry for the synthesis of certain drugs, particularly those that require specific functional groups. It is also used in the polymer industry as a monomer or intermediate. Additionally, it finds applications in the development of sensors and semiconductors due to its unique chemical properties.

What precautions should be taken when handling 6-Hydroxy-3-pyridazinecarboxylic acid (CAS: 37972-69-3)?

When handling 6-Hydroxy-3-pyridazinecarboxylic acid (CAS: 37972-69-3), it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. It should be stored in a fume hood to minimize inhalation risks. In case of a spill, it should be cleaned up with caution, using appropriate spill kits or neutralizing agents as needed. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.