Oxybis(2,1-ethanediyloxy-2,1-ethanediyl) bis(4-methylbenzenesulfonate) | CAS No. 37860-51-8

Oxybis(2,1-ethanediyloxy-2,1-ethanediyl) bis(4-methylbenzenesulfonate)

Basic Information

CAS Number

37860-51-8

Molecular Formula

C22H30O9S2

Molecular Weight

502.61 g/mol

AD

Basic Physical Properties

Refractive Index

n20/D 1.53(lit.)

CC1=CC=C(C=C1)S(=O)(=O)OCCOCCOCCOCCOS(=O)(=O)C2=CC=C(C=C2)C

InChI

InChI=1S/C22H30O9S2/c1-19-3-7-21(8-4-19)32(23,24)30-17-15-28-13-11-27-12-14-29-16-18-31-33(25,26)22-9-5-20(2)6-10-22/h3-10H,11-18H2,1-2H3

InChIKey

SLAONPBUWDUSSO-UHFFFAOYSA-N

LogP

2.4640400000000007

Topological Polar Surface Area

114.43 Ų

Hydrogen Bond Donor/Acceptor

0 / 9

Complexity

650

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

  • Tetraethylene glycol ditosylate
  • ((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl)bis(4-methylbenzenesulfonate)
  • Tetraethylene glycol di(p-toluenesulfonate), purum, >=95.0% (HPLC), colorless to yellow
  • SLAONPBUWDUSSO-UHFFFAOYSA-N
  • 37860-51-8
  • J-500008
  • SY037072
  • Z56791661
  • HY-W004816
  • SCHEMBL1145153
  • 2-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate
  • Tos-PEG5-Tos
  • ((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(4-methylbenzene sulfonate)
  • UPCMLD0ENAT0504-1282:001
  • O,O'-ditosyl-3,6,9-trioxaundecane-1,11-diol
  • T1493
  • Tetraethylene Glycol Bis(p-toluenesulfonate)
  • AKOS002312305
  • 2-[2-(2-{2-[(4-ethoxy}ethoxy)ethoxy]ethyl 4-methylbenzene-1-sulfonate
  • ((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(4-methylbenzenesulfonate)
  • H10023
  • PROTAC Linker 16
  • CS-W004816
  • Tetraethylene Glycol Di-p-tosylate
  • 2,2'-(Ethylenedioxy)triethyl ditosylate
  • MFCD00075239
  • Bis-Tos-PEG4
  • Bis[2-(2-tosyloxyethoxy)ethyl] Ether
  • DS-2513
  • Bis[2-[2-(p-toluenesulfonyloxy)ethoxy]ethyl] Ether
  • 2-[2-(2-{2-[(4-methylbenzenesulfonyl)oxy]ethoxy}ethoxy)ethoxy]ethyl 4-methylbenzene-1-sulfonate

MDL Number

MFCD00075239

Customs Code

2909309090

FAQ

What are the physical and chemical properties of Oxybis(2,1-ethanediyloxy-2,1-ethanediyl) bis(4-methylbenzenesulfonate) (CAS: 37860-51-8)?

Oxybis(2,1-ethanediyloxy-2,1-ethanediyl) bis(4-methylbenzenesulfonate) (CAS: 37860-51-8) is a solid with a crystalline form. The molecular weight is approximately 534.5 g/mol. It has limited solubility in water but is soluble in organic solvents. This compound is less reactive under normal conditions but can undergo electrophilic substitution reactions. It is stable under normal storage conditions but should be protected from moisture and heat.

How is Oxybis(2,1-ethanediyloxy-2,1-ethanediyl) bis(4-methylbenzenesulfonate) (CAS: 37860-51-8) typically synthesized?

Oxybis(2,1-ethanediyloxy-2,1-ethanediyl) bis(4-methylbenzenesulfonate) is typically synthesized by the condensation of 4-methylbenzenesulfonic acid with ethylene glycol, followed by bis-esterification. Commonly used catalysts include strong acids like sulfuric acid. The reaction yields high selectivity and good yield, with purification steps involving recrystallization and filtration.

What industries use Oxybis(2,1-ethanediyloxy-2,1-ethanediyl) bis(4-methylbenzenesulfonate) (CAS: 37860-51-8)?

Oxybis(2,1-ethanediyloxy-2,1-ethanediyl) bis(4-methylbenzenesulfonate) (CAS: 37860-51-8) is used in the pharmaceutical industry for synthesizing certain drug intermediates, in the polymer industry for the synthesis of specific monomers, and in the sensor industry for constructing detection devices. It is also utilized in the semiconductor industry for certain purification processes.

What precautions should be taken when handling Oxybis(2,1-ethanediyloxy-2,1-ethanediyl) bis(4-methylbenzenesulfonate) (CAS: 37860-51-8)?

When handling Oxybis(2,1-ethanediyloxy-2,1-ethanediyl) bis(4-methylbenzenesulfonate) (CAS: 37860-51-8), wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coat. Work in a well-ventilated area or a fume hood. Avoid contact with skin and eyes. In case of a spill, use appropriate spill cleanup materials and consult the Safety Data Sheet (SDS) for specific instructions. Store the compound in a cool, dry place away from moisture and heat sources.

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