methyl (2R)-2-amino-2-(4-hydroxyphenyl)acetate

Basic Information

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CAS Number

37763-23-8

Molecular Formula

C9H11NO3

Molecular Weight

181.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

180-184°C

Boiling Point

335.7 °C at 760 mmHg

Density

1.248

Flash Point

156.9 °C

Refractive Index

1.57

Specific Rotation

-128 ~ -135° (c=1, 2N HCl)

SMILES

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COC(=O)C(C1=CC=C(C=C1)O)N

InChI

InChI=1S/C9H11NO3/c1-13-9(12)8(10)6-2-4-7(11)5-3-6/h2-5,8,11H,10H2,1H3/t8-/m1/s1

InChIKey

SZBDOFWNZVHVGR-MRVPVSSYSA-N

LogP

0.565

Topological Polar Surface Area

72.55 Å²

Hydrogen Bond Donor/Acceptor

3 / 4

Complexity

176

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

37763-23-8
(R)-Methyl2-amino-2-(4-hydroxyphenyl)acetate
Methyl D-(-)-4-hydroxy-phenylglycinate
SCHEMBL1143624
(R)-Methyl 2-amino-2-(4-hydroxyphenyl)acetate
EN300-2053074
AKOS015920010
Methyl D-(-)-4-hydroxyphenylglycinate
AS-13487
methyl (2R)-2-amino-2-(4-hydroxyphenyl)acetate
CS-W021142
SZBDOFWNZVHVGR-MRVPVSSYSA-N
37763-23-8 (free base)
Methyl (R)-2-amino-2-(4-hydroxyphenyl)acetate
Benzeneacetic acid, a-amino-4-hydroxy-, methyl ester, (aR)-
MFCD07778088
D-(-)-alpha-p-Hydroxy-phenylglycine methyl ester
D-4-Hydroxyphenylglycine methyl ester
D-(-)-A-P-HYDROXY PHENYLGLYCINE METHYL ESTER
Methyl (R)-(-)-Amino(4-Hydroxyphenyl)Acetate
methyl (R)-2-amino-2-(4-hydroxyphenyl)acetate

MDL Number

MFCD07778088

Customs Code

2942000000

FAQ

What is methyl (2R)-2-amino-2-(4-hydroxyphenyl)acetate (CAS: 37763-23-8)?

Methyl (2R)-2-amino-2-(4-hydroxyphenyl)acetate is a chiral compound with a molecular formula of C8H12NO3. It is a derivative of acetic acid with a hydroxyl group at the 4-position of the phenyl ring and an amino group attached to the acetate group. This compound is used in pharmaceuticals and research due to its chiral nature and structural features.

What are the main uses of methyl (2R)-2-amino-2-(4-hydroxyphenyl)acetate (CAS: 37763-23-8)?

Methyl (2R)-2-amino-2-(4-hydroxyphenyl)acetate is primarily used in the pharmaceutical industry as an intermediate in the synthesis of chiral compounds. It is also used in research for its structural features and chiral properties, and occasionally in some industrial applications for its chemical reactivity.

Is methyl (2R)-2-amino-2-(4-hydroxyphenyl)acetate (CAS: 37763-23-8) safe?

Methyl (2R)-2-amino-2-(4-hydroxyphenyl)acetate is generally considered safe when handled properly. However, it may cause skin irritation and should be stored and used in a well-ventilated area. Protective gloves and eyewear are recommended. The compound should be kept away from strong acids and bases to prevent degradation.

How should methyl (2R)-2-amino-2-(4-hydroxyphenyl)acetate (CAS: 37763-23-8) be stored?

Methyl (2R)-2-amino-2-(4-hydroxyphenyl)acetate should be stored in a cool, dry place, away from direct sunlight and sources of heat. It should be kept in a tightly sealed container made of appropriate materials to prevent moisture absorption and contamination. The storage temperature should be below 25°C (77°F) to maintain stability. Avoid contact with incompatible materials such as strong acids and bases.