(3R)-3-Piperidinylmethanol

Basic Information

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CAS Number

37675-20-0

Molecular Formula

C6H13NO

Molecular Weight

115.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

240.4±0.0 ºC (760 Torr),

Flash Point

92.3±10.5 ºC,

Refractive Index

1.451

SMILES

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C1CC(CNC1)CO

InChI

InChI=1S/C6H13NO/c8-5-6-2-1-3-7-4-6/h6-8H,1-5H2/t6-/m1/s1

InChIKey

VUNPWIPIOOMCPT-ZCFIWIBFSA-N

LogP

-0.02170000000000022

Topological Polar Surface Area

32.26 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

65.5

Synonyms & References

English

3-Piperidinemethanol, (3R)-
(R)-(Piperidin-3-yl)methanol
(R)-3-(hydroxymethyl)piperidine
VUNPWIPIOOMCPT-ZCFIWIBFSA-N
FS-5169
CS-W018674
A823823
SCHEMBL1484698
3-(R)-hydroxymethyl-piperidine
(3R)-Piperidinemethanol
(R)-3-Piperidinemethanol
3(R)-PIPERIDINEMETHANOL
AKOS006329224
[(3R)-piperidin-3-yl]methanol
(R)-PIPERIDIN-3-YLMETHANOL
EN300-107953
(R)-3-Hydroxymethyl-piperidine
37675-20-0
DTXSID80357382
F14592
3(R)-Piperidinemethanol
3-Piperidinemethanol,(3R)-
C6H13NO
(3R)-piperidin-3-ylmethanol
(R)-(+)-3-piperidinylmethanol
3-Piperidinemethanol,(3R)
R-3-hydroxymethyl piperidine
(R)-(+)-3-(Hydroxymethyl)piperidine
(R)-(+)-3-Piperidinemethanol
(R)-Piperidin-3-ylmethanol
((R)-piperidin-3-yl)methanol

MDL Number

MFCD09751036

Customs Code

2933399090

FAQ

What are the physical and chemical properties of (3R)-3-Piperidinylmethanol (CAS: 37675-20-0)?

(3R)-3-Piperidinylmethanol is a colorless liquid with a molecular weight of approximately 115.17 g/mol. It has a low solubility in water but is soluble in organic solvents. This compound is mildly basic due to its hydroxyl group and exhibits some reactivity with acidic substances. It is crystalline at room temperature and can be used in the synthesis of various pharmaceuticals and agrochemicals.

How is (3R)-3-Piperidinylmethanol (CAS: 37675-20-0) typically synthesized?

(3R)-3-Piperidinylmethanol can be synthesized through the reduction of 3-(1-pyrrolidinyl)propionaldehyde using hydrogen and a catalyst such as palladium on carbon. The reaction is performed under mild conditions to achieve high selectivity and yield, making it a common method in organic synthesis for preparing this compound.

What industries use (3R)-3-Piperidinylmethanol (CAS: 37675-20-0)?

(3R)-3-Piperidinylmethanol is primarily used in the pharmaceutical industry for the synthesis of drug candidates and intermediates. It is also utilized in the agrochemical industry for developing pesticides and herbicides. Additionally, it has applications in the production of certain polymers and as a reagent in analytical chemistry and chemical sensors.

What precautions should be taken when handling (3R)-3-Piperidinylmethanol (CAS: 37675-20-0)?

When handling (3R)-3-Piperidinylmethanol, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store the compound in a cool, dry place away from direct sunlight and flammable materials. Use a fume hood during manipulation to minimize exposure. In case of a spill, use appropriate absorbents and follow the safety data sheet (SDS) guidelines for disposal.