3'-{2-[1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene]hydrazino}-2'-hydroxy-3-biphenylcarboxylic acid | CAS No. 376591-99-0

3'-{2-[1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene]hydrazino}-2'-hydroxy-3-biphenylcarboxylic acid

Basic Information

CAS Number

376591-99-0

Molecular Formula

C25H22N4O4

Molecular Weight

442.48 g/mol

AD

Basic Physical Properties

Solubility

Insuluble (2.1E-3 g/L) (25 ºC),

CC1=NN(C(=O)C1=NNc2cccc(c2O)c3cccc(c3)C(=O)O)c4ccc(C)c(C)c4

InChI

InChI=1S/C25H22N4O4/c1-14-10-11-19(12-15(14)2)29-24(31)22(16(3)28-29)27-26-21-9-5-8-20(23(21)30)17-6-4-7-18(13-17)25(32)33/h4-13,26,30H,1-3H3,(H,32,33)

InChIKey

XDXWLKQMMKQXPV-UHFFFAOYSA-N

LogP

4.564840000000003

Topological Polar Surface Area

114.59000000000002 Ų

Hydrogen Bond Donor/Acceptor

3 / 8

Complexity

812

Synonyms & References

English

  • 3'-[[1-(3,4-二甲基苯基)-1,5-二氢-3-甲基-5-氧代-4H-吡唑-4-亚基]肼基]-2'-羟基-[1,1'-联苯]-3-羧酸
  • 3'-[[1-(3,4-DiMethylphenyl)-1,5-dihydro-3-Methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazino]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid
  • 3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid
  • Eltrombopag
  • Promacta
  • (Z)-3'-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid
  • SB497115
  • (ZE)-Eltrombopag
  • Eltrombopag free base
  • S56D65XJ9G
  • 3'-[2-[(2Z)-1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid
  • (Z)-3'
  • Eltrombopag Impurity 42
  • 3'-{2-1-(3,4-dimethylphenyl)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-4-ylidenehydrazin-1-yl}-2'-hydroxy-1,1'-biphenyl-3-carboxylic acid

MDL Number

MFCD20926253

FAQ

What is 3'-{2-[1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene]hydrazino}-2'-hydroxy-3-biphenylcarboxylic acid (CAS: 376591-99-0)?

3'-{2-[1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene]hydrazino}-2'-hydroxy-3-biphenylcarboxylic acid is a complex organic compound with a unique chemical structure. It contains a biphenyl backbone with a specific hydrazine derivative linked to its structure, making it a potential candidate for pharmaceutical and chemical applications.

What are the main uses of 3'-{2-[1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene]hydrazino}-2'-hydroxy-3-biphenylcarboxylic acid (CAS: 376591-99-0)?

3'-{2-[1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene]hydrazino}-2'-hydroxy-3-biphenylcarboxylic acid finds applications in pharmaceutical research as a potential drug candidate, and it may also be used in the synthesis of other specialized chemicals for industrial purposes.

Is 3'-{2-[1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene]hydrazino}-2'-hydroxy-3-biphenylcarboxylic acid (CAS: 376591-99-0) safe?

Safety depends on proper handling and use. This compound should be used in a well-ventilated area and with appropriate personal protective equipment. It is important to follow safety guidelines and handle it with care to prevent exposure and potential health risks.

How should 3'-{2-[1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene]hydrazino}-2'-hydroxy-3-biphenylcarboxylic acid (CAS: 376591-99-0) be stored?

This compound should be stored in a cool, dry place, away from direct sunlight and heat sources. It is advisable to keep it in a tightly sealed container and avoid contact with moisture to prevent degradation. Store it under appropriate conditions to ensure stability and safety during use.

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