2-(Trifluoromethoxy)benzenesulfonamide

Basic Information

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CAS Number

37526-59-3

Molecular Formula

C7H6F3NO3S

Molecular Weight

241.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

185.0 to 190.0 deg-C

Boiling Point

312.4°C at 760 mmHg

Flash Point

142.7℃

Refractive Index

1.49

SMILES

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C1=CC=C(C(=C1)OC(F)(F)F)S(=O)(=O)N

InChI

InChI=1S/C7H6F3NO3S/c8-7(9,10)14-5-3-1-2-4-6(5)15(11,12)13/h1-4H,(H2,11,12,13)

InChIKey

HIFGQHGWMTZMOH-UHFFFAOYSA-N

LogP

1.2326

Topological Polar Surface Area

69.39 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

308

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

Benzenesulfonamide, 2-(trifluoromethoxy)-
CHEMBL3188268
FT-0639379
PS-7573
AKOS000137761
UNII-3DQ25354MB
CS-0041598
MFCD01320751
DTXCID9024930
SY018621
CAS-37526-59-3
37526-59-3
2-(Trifluoromethoxy)benzenesulfonamide, AldrichCPR
J-506652
NCGC00256150-01
A823725
2-trifluoromethoxybenzene sulphonamide
EN300-245385
2-trifluoromethoxy-benzene-sulphonic acid amide
2-Trifluoromethoxy benzenesulfonamide
3DQ25354MB
DTXSID1044930
Tox21_301693
2-Triflourmethoxybenzolsulfonamid
AM20040316
2-(trifluoromethoxy)benzene-1-sulfonamide
ZB1785
2-(trifluoromethyloxy)benzenesulfonamide
T2604
2-(Trifluoromethoxy)benzenesulfonamide
SCHEMBL692280

MDL Number

MFCD01320751

Customs Code

2935009090

FAQ

What regulatory guidelines apply to 2-(Trifluoromethoxy)benzenesulfonamide (CAS: 37526-59-3)?

2-(Trifluoromethoxy)benzenesulfonamide (CAS: 37526-59-3) falls under the scope of the GHS (Globally Harmonized System of Classification and Labelling of Chemicals) which categorizes it as a hazardous substance. For chemical manufacturers and importers in the European Union, it is also subject to the REACH regulations. In the USA, it is regulated by the FDA and the EPA concerning environmental and health safety. It is essential to comply with all local and international regulations when handling this compound.

Are there alternatives to 2-(Trifluoromethoxy)benzenesulfonamide (CAS: 37526-59-3) in synthesis?

Several alternatives can be used in the synthesis of 2-(Trifluoromethoxy)benzenesulfonamide (CAS: 37526-59-3). For instance, trifluoromethoxybenzenesulfonamides with different substituents or other functional groups can serve as viable alternatives. Additionally, related compounds such as benzenesulfonamides or trifluoromethoxybenzenesulfonamides with variations in the aromatic ring can also be explored as alternatives.

What is the market or research trend for 2-(Trifluoromethoxy)benzenesulfonamide (CAS: 37526-59-3)?

The market for 2-(Trifluoromethoxy)benzenesulfonamide (CAS: 37526-59-3) is growing as it is increasingly used in pharmaceutical applications, particularly in the synthesis of new drug candidates. Research trends indicate a focus on its use as a key intermediate in drug discovery and development. Additionally, there is a rising interest in its application in materials science, where its unique chemical properties are being explored.

How should waste containing 2-(Trifluoromethoxy)benzenesulfonamide (CAS: 37526-59-3) be handled?

Waste containing 2-(Trifluoromethoxy)benzenesulfonamide (CAS: 37526-59-3) should be collected in appropriate containers and stored in a well-ventilated area until disposal. Incineration is a common method of disposal, but it should be conducted in an enclosed incinerator to minimize the release of harmful gases. Alternatively, professional waste disposal services can be utilized to ensure compliance with environmental regulations. Proper personal protective equipment and safety measures should be followed to protect the environment and human health.