(Z)-N-Hydroxy-1-(4-methoxyphenyl)methanimine | CAS No. 3717-22-4

(Z)-N-Hydroxy-1-(4-methoxyphenyl)methanimine

Basic Information

CAS Number

3717-22-4

Molecular Formula

C8H9NO2

Molecular Weight

151.16 g/mol

AD

Basic Physical Properties

COC1=CC=C(C=C1)C=NO

InChI

InChI=1S/C8H9NO2/c1-11-8-4-2-7(3-5-8)6-9-10/h2-6,10H,1H3/b9-6-

InChIKey

FXOSHPAYNZBSFO-TWGQIWQCSA-N

LogP

1.5032999999999999

Topological Polar Surface Area

41.82 Ų

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

128

Synonyms & References

English

  • NSC 44
  • DTXSID901303874
  • MFCD00137433
  • p-Methoxybenzaldoxime
  • p-Anisaldehyde, oxime
  • anti-p-Anisaldoxime
  • AS-45340
  • (E)-4-Methoxybenzaldehydeoxime
  • syn-p-Anisaldoxime
  • 4-Methoxybenzaldehyde oxime
  • NSC-44
  • (NZ)-N-[(4-methoxyphenyl)methylidene]hydroxylamine
  • NSC44
  • Benzaldehyde, 4-methoxy-, oxime, (E)-
  • FXOSHPAYNZBSFO-RMKNXTFCSA-N
  • (Z)-4-Methoxybenzaldehyde oxime
  • NSC-136033
  • 4-Methoxy-benzaldoxim
  • p-Methoxy-anti-benzaldoxime
  • SCHEMBL1566907
  • (1E)-4-methoxybenzaldehyde oxime
  • AKOS000503115
  • A913902
  • p-Anisaldehyde oxime
  • 4-Methoxybenzaldoxime
  • EINECS 221-788-4
  • CS-0369380
  • EN300-06090
  • p-Methoxybenzaldehyde oxime
  • NSC136033
  • Benzaldehyde, 4-methoxy-, oxime

MDL Number

MFCD00137433

FAQ

What are the physical and chemical properties of (Z)-N-Hydroxy-1-(4-methoxyphenyl)methanimine (CAS: 3717-22-4)?

(Z)-N-Hydroxy-1-(4-methoxyphenyl)methanimine is a crystalline solid with a molecular weight of approximately 228.2 g/mol. It is slightly soluble in water but more soluble in organic solvents like methanol and acetonitrile. The compound is moderately reactive, particularly in acidic conditions, making it susceptible to hydrolysis.

How is (Z)-N-Hydroxy-1-(4-methoxyphenyl)methanimine (CAS: 3717-22-4) typically synthesized?

(Z)-N-Hydroxy-1-(4-methoxyphenyl)methanimine is often synthesized via a multistep process involving the condensation of 4-methoxybenzaldehyde with hydroxylamine, followed by reductive amination. The reaction typically requires mild acid catalysis and is known for its high yield and good selectivity.

What industries use (Z)-N-Hydroxy-1-(4-methoxyphenyl)methanimine (CAS: 3717-22-4)?

(Z)-N-Hydroxy-1-(4-methoxyphenyl)methanimine finds applications in the pharmaceutical industry for the synthesis of drug intermediates, as well as in the polymer industry for the development of novel materials. It is also utilized in the production of sensors and semiconductors due to its unique chemical properties.

What precautions should be taken when handling (Z)-N-Hydroxy-1-(4-methoxyphenyl)methanimine (CAS: 3717-22-4)?

Handling (Z)-N-Hydroxy-1-(4-methoxyphenyl)methanimine requires the use of personal protective equipment (PPE), including gloves, goggles, and a lab coat. It should be stored in a cool, dry place, away from sources of heat and moisture. Spills should be cleaned up immediately using appropriate spill kits, and the area should be well-ventilated. Always consult the Safety Data Sheet (SDS) for specific handling and disposal instructions.

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