2-Fluoroethanol

Basic Information

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CAS Number

371-62-0

Molecular Formula

C2H5FO

Molecular Weight

64.06 g/mol

Chemical Classification

Fine Chemicals Specialty Chemicals UV Stabilizers

Electronic Chemicals Semiconductor Materials Etchants

Water Treatment Chemicals Disinfectants Chlorine Compounds

Basic Physical Properties

Melting Point

−26.5 °C

Boiling Point

102-104℃

Flash Point

31℃(87℉)(lit.)

Solubility

Fully miscible.

Refractive Index

n20/D 1.365(lit.)

Vapor Pressure

16 mm Hg ( 20 °C)

SMILES

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C(CF)O

InChI

InChI=1S/C2H5FO/c3-1-2-4/h4H,1-2H2

InChIKey

GGDYAKVUZMZKRV-UHFFFAOYSA-N

LogP

-0.05179999999999996

Topological Polar Surface Area

20.23 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

Safety Information

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GHS Hazard Pictograms

H226

H300

H310

H330

Hazard Statement

H226 Flammable liquid and vapor
Flammable liquids

H300 Fatal if swallowed
Acute toxicity, oral

H310 Fatal in contact with skin
Acute toxicity, dermal

H330 Fatal if inhaled
Acute toxicity, inhalation

Hazard Class

Class 6.1 Class 6.1

Sensitiveness

Air Sensitive

Synonyms & References

English

2-FLUORO-1-ETHANOL [HSDB]
2-Fluoroethanol
CH2FCH2OH
InChI=1/C2H5FO/c3-1-2-4/h4H,1-2H
2-Fluoroethanol, 95%
AMY25659
2-Fluoro-ethanol
2-Fluoro-1-ethanol
HSDB 6389
AKOS004904101
EINECS 206-740-2
Monofluorethanol
beta-Fluoroethanol
NS00041465
ETHYLENE FLUOROHYDRIN
.beta.-Fluoroethanol
371-62-0
DTXSID0059902
Ethanol, 2-fluoro-
2-fluoroethan-1-ol
BRN 1730857
BP-11368
NSC158283
NSC-158283
2-fluoroethane-1-ol
CHEMBL115586
Q209389
TL 741
UNII-4M427A5HML
GS-3504
4M427A5HML

MDL Number

MFCD00002828

Customs Code

2905590090

FAQ

What are the physical and chemical properties of 2-Fluoroethanol (CAS: 371-62-0)?

2-Fluoroethanol (CAS: 371-62-0) is a colorless liquid with a molecular weight of 98.03 g/mol. It is slightly soluble in water and miscible with most organic solvents. Chemically, it is highly reactive, especially towards nucleophilic substitution reactions. It has a boiling point of 97.8°C and a melting point of -72.6°C.

How is 2-Fluoroethanol (CAS: 371-62-0) typically synthesized?

2-Fluoroethanol is typically synthesized by the reaction of ethylene oxide with hydrogen fluoride. This process involves the selective hydrolysis of ethylene oxide with an acid catalyst to form 2-fluoroethanol. The reaction is conducted under controlled conditions to maximize yield and selectivity.

What industries use 2-Fluoroethanol (CAS: 371-62-0)?

2-Fluoroethanol (CAS: 371-62-0) is used in various industries, including pharmaceuticals for the synthesis of drugs, as a solvent in organic synthesis, and in the production of polymers. It is also utilized in the development of sensors and as an intermediate in semiconductor manufacturing processes.

What precautions should be taken when handling 2-Fluoroethanol (CAS: 371-62-0)?

When handling 2-Fluoroethanol (CAS: 371-62-0), it is essential to use personal protective equipment (PPE) such as gloves, goggles, and lab coats. The substance should be handled in a well-ventilated area or a fume hood to minimize exposure. Proper spill containment and disposal methods should be followed, and safety data sheets (SDS) should be consulted for detailed handling instructions and emergency procedures.