2,5-Dimethoxy-4(1H)-pyrimidinone

Basic Information

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CAS Number

370103-23-4

Molecular Formula

C6H8N2O3

Molecular Weight

156.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

SMILES

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O=C1NC(OC)=NC=C1OC

InChI

InChI=1S/C6H8N2O3/c1-10-4-3-7-6(11-2)8-5(4)9/h3H,1-2H3,(H,7,8,9)

InChIKey

JEARLRMCZMBVFC-UHFFFAOYSA-N

LogP

-0.2129000000000001

Topological Polar Surface Area

64.21000000000001 Å²

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

232

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

2,5-Dimethoxypyrimidin-4(3H)-one
2,5-dimethoxy-1H-pyrimidin-6-one
2,5-dimethoxy-4(3H)-Pyrimidinone
2,5-DIMETHOXY-4-HYDROXYPYRIMIDINE
AK126855
FCH3738764
AX8248646

MDL Number

MFCD20480733

FAQ

What regulatory guidelines apply to 2,5-Dimethoxy-4(1H)-pyrimidinone (CAS: 370103-23-4)?

2,5-Dimethoxy-4(1H)-pyrimidinone (CAS: 370103-23-4) is subject to various regulatory guidelines including GHS classification, REACH regulations, and FDA/EPA requirements. GHS classifies it as a hazardous substance based on its reactivity. REACH requires manufacturers and importers to register the substance if the annual manufacture or import exceeds one tonne. FDA regulates its use in pharmaceuticals, while EPA oversees its use in consumer products and environmental handling.

Are there alternatives to 2,5-Dimethoxy-4(1H)-pyrimidinone (CAS: 370103-23-4) in synthesis?

Alternatives to 2,5-Dimethoxy-4(1H)-pyrimidinone (CAS: 370103-23-4) in synthesis include 2,5-Dimethoxy-4(1H)-pyrimidin-4-one and similar pyrimidinone derivatives. Common alternative reagents like piperidine, dimethyl sulfoxide (DMSO), and acetic anhydride can be used as substitutes depending on the specific reaction conditions. These alternatives can offer similar functionalities but with different reactivity profiles.

What is the market or research trend for 2,5-Dimethoxy-4(1H)-pyrimidinone (CAS: 370103-23-4)?

The market for 2,5-Dimethoxy-4(1H)-pyrimidinone (CAS: 370103-23-4) is growing due to its applications in pharmaceuticals, agrochemicals, and research. Recent trends indicate increased interest in its use as a building block in medicinal chemistry and as a scaffold for drug discovery. Research is focusing on its potential in treating neurological disorders and as a precursor for synthesizing complex molecules.

How should waste containing 2,5-Dimethoxy-4(1H)-pyrimidinone (CAS: 370103-23-4) be handled?

Waste containing 2,5-Dimethoxy-4(1H)-pyrimidinone (CAS: 370103-23-4) should be collected in appropriate containers and stored under controlled conditions to prevent degradation. Incineration is a common method for disposal, ensuring complete combustion to minimize environmental impact. Alternatively, professional waste disposal services can handle the waste safely. Environmental protection measures include proper ventilation and safety gear to protect against potential inhalation or skin contact. Compliance with local regulations is crucial for safe waste management.