4-Bromo-2-pyridinol

Basic Information

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CAS Number

36953-37-4

Molecular Formula

C5H4BrNO

Molecular Weight

174 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Physical State

Crystalline Powder

Melting Point

207.0 to 211.0 deg-C

Boiling Point

305.9°C at 760 mmHg

Density

1.776

Flash Point

138.8℃

Refractive Index

1.543

SMILES

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C1=CNC(=O)C=C1Br

InChI

InChI=1S/C5H4BrNO/c6-4-1-2-7-5(8)3-4/h1-3H,(H,7,8)

InChIKey

SSLMGOKTIUIZLY-UHFFFAOYSA-N

LogP

1.5496999999999999

Topological Polar Surface Area

33.120000000000005 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

171

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

B4383
4-Bromo-2-hydroxyopyridine
A6357
BCP01174
MFCD00234041
SSLMGOKTIUIZLY-UHFFFAOYSA-N
4-bromo pyridone
HY-65036
A823478
4-BROMO-1,2-DIHYDROPYRIDIN-2-ONE
4-bromanyl-1H-pyridin-2-one
4-BROMO-2-HYDROXYPYRIDINE
36953-37-4
4-Bromopyridin-2(1H)-one
PB17828
4-Bromo-2-pyridone
FT-0600216
A874242
AMY7930
4-Bromo-pyridin-2-ol
GS-0909
AKOS006343464
SCHEMBL117262
SY013311
AC-23518
4-bromopyridone
FT-0617798
4-bromo-1 H-pyridin-2-one
4-bromanyl-1~{H}-pyridin-2-one
EN300-87234
DTXSID00355749

MDL Number

MFCD00234041

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 4-Bromo-2-pyridinol (CAS: 36953-37-4)?

4-Bromo-2-pyridinol is a white crystalline solid with a molecular weight of approximately 177.03 g/mol. It is slightly soluble in water and more soluble in organic solvents. The compound shows moderate reactivity towards nucleophiles and can undergo substitution reactions. It has a melting point of around 135-137°C and a boiling point of about 210-212°C under reduced pressure.

How is 4-Bromo-2-pyridinol (CAS: 36953-37-4) typically synthesized?

4-Bromo-2-pyridinol is commonly synthesized via the bromination of 2-pyridol followed by hydrolysis of the bromopyridyl derivative. Commonly used brominating agents include phosphorus tribromide or bromine in the presence of appropriate solvents. The reaction is typically carried out under anhydrous conditions to improve yield and purity.

What industries use 4-Bromo-2-pyridinol (CAS: 36953-37-4)?

4-Bromo-2-pyridinol is used in various industries, particularly in pharmaceuticals for the synthesis of certain drug intermediates. It also finds applications in the preparation of dyes and pigments, as well as in research for its potential use as a chemosensor and in organic electronics.

What precautions should be taken when handling 4-Bromo-2-pyridinol (CAS: 36953-37-4)?

Proper protective equipment such as gloves, safety goggles, and a lab coat should be worn when handling 4-Bromo-2-pyridinol. Work should be conducted in a well-ventilated fume hood to minimize inhalation risks. Spills should be contained and cleaned up using appropriate absorbent materials, followed by thorough decontamination. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.