5-Chloro-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-1,3-oxazolidin-5-yl}methyl)-2-thiophenecarboxamide

Basic Information

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CAS Number

366789-02-8

Molecular Formula

C19H18ClN3O5S

Molecular Weight

435.89 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Physical State

Powder

Melting Point

228-234°C

Boiling Point

732.6°C at 760 mmHg

Solubility

In water, 25.05 mg/L at 25 °C (est)

Vapor Pressure

6.66X10-16 mm Hg at 25 °C (est)

Odor

Odorless

Specific Rotation

-41° (c=0.3, DMSO)

SMILES

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c1cc(ccc1N2CCOCC2=O)N3C[C@@H](OC3=O)CNC(=O)c4ccc(s4)Cl

InChI

InChI=1S/C19H18ClN3O5S/c20-16-6-5-15(29-16)18(25)21-9-14-10-23(19(26)28-14)13-3-1-12(2-4-13)22-7-8-27-11-17(22)24/h1-6,14H,7-11H2,(H,21,25)/t14-/m0/s1

InChIKey

KGFYHTZWPPHNLQ-AWEZNQCLSA-N

LogP

2.5199

Topological Polar Surface Area

88.18 Å²

Hydrogen Bond Donor/Acceptor

1 / 8

Complexity

645

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(S)-5-Chloro-N-((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)thiophene-2-carboxamide
(S)-Rivaroxaban
(S)-5-Chloro-N-((2-oxo-3-(4-(3-oxomorpholino)phenyl)-oxazolidin-5-yl)methyl)thiophene-2-carbox
RIVAROXABAN STAGE-IV [5-CHLORO-N-({5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL)PHENYL]-1,3-OXAZOLIDIN-5-YL}-METHYL)-2(AS PER INV
Rivaroxaban Isomer
5-Chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide
BAY 59-7939
Rivaroxaban
5-Chloro-N-(((5S)-2-oxo-3-(4-(3-oxomorpholin-4-yl)phenyl)-1,3-oxazolidin-5-yl)methyl)thiophene-2-carboxamide
Rivaroxaban Xarelto
(S)-5-Chloro-N-((2-oxo-3-(4-(3-oxomorpholino)phenyl)-oxazolidin-5-yl)methyl)thiophene-2-carboxamide
Rivarobaxan
rivaraoxaban
Rivaroxaba
Xarelto
Rivaroxaban Imp
9NDF7JZ4M3
C19H18ClN3O5S
5-Chloro-N-({(5s)-2-Oxo-3-[4-(3-Oxomorpholin-4-Yl)phenyl]-1,3-Oxazolidin-5-Yl}methyl)thiophene-2-Carboxamide
Rivaroxaban, 98%
Rivaroxaban (Xarelto)
5-chloro-N-[[(5
5-CHLORO-N-[[(S)-3-(4-(3-OXOMORPHOLIN-4-YL)PHENYL)-2-OXO-1,3-OXAZOLIDIN-5-YL]METHYL]-THIOPHENE-2-CARBOXAMIDE
5-Chloro-N-(((5
2-Thiophenecarboxamide, 5-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-
5-Chloro-N-(((5S)-
T5SJ BG EVM1- DT5NVOTJ AR D- AT6NV DOTJ &&S Form
(S)-5-Chloro-N-((2-oxo-3-(4-(3-oxomorpholino)phenyl)-oxazolidin-5-yl)methyl )thiophene-2-carboxamide
bay 59-7939 (rivaroxaban)
BAY 59-7939|Xarelto®
BAY59-7939

MDL Number

MFCD11974010

FAQ

What is 5-Chloro-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-1,3-oxazolidin-5-yl}methyl)-2-thiophenecarboxamide (CAS: 366789-02-8)?

5-Chloro-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-1,3-oxazolidin-5-yl}methyl)-2-thiophenecarboxamide (CAS: 366789-02-8) is a complex organic compound containing a thiophene ring, chloro group, and a substituted oxazolidine moiety. Its molecular formula is C17H17ClN3O5S, with a molecular weight of approximately 416.8 g/mol. The compound exhibits solubility in polar solvents and is characterized by its functional groups, making it relevant in chemical synthesis and pharmaceutical research.

What are the main uses of 5-Chloro-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-1,3-oxazolidin-5-yl}methyl)-2-thiophenecarboxamide (CAS: 366789-02-8)?

This compound is primarily used in pharmaceutical research as a potential drug candidate, particularly in the development of anti-inflammatory or antiviral agents. Its unique structure, combining thiophene and morpholine functionalities, makes it valuable for synthesizing bioactive molecules. It may also find applications in organic chemistry as an intermediate for further modifications, though specific industrial or food uses are not widely documented.

Is 5-Chloro-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-1,3-oxazolidin-5-yl}methyl)-2-thiophenecarboxamide (CAS: 366789-02-8) safe?

Safety of this compound depends on its specific application and exposure conditions. As a chemical with potential reactivity, it requires careful handling to avoid skin or eye contact. Limited toxicity data exists, but standard safety precautions, such as using gloves and ensuring proper ventilation, are recommended. Always refer to safety data sheets (SDS) for detailed guidelines on its hazards and protective measures.

How should 5-Chloro-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-1,3-oxazolidin-5-yl}methyl)-2-thiophenecarboxamide (CAS: 366789-02-8) be stored?

Store this compound in a cool, dry place (ideally 2-8°C), away from light and moisture. Use airtight, corrosion-resistant containers to maintain stability. Avoid exposure to air and incompatible substances to prevent degradation. Keep it in a well-ventilated area and follow manufacturer guidelines for long-term storage to ensure safety and efficacy.