4-(2-Chloroethyl)morpholine hydrochloride (1:1)

Basic Information

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CAS Number

3647-69-6

Molecular Formula

C6H13Cl2NO

Molecular Weight

186.08 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

183.0 to 187.0 deg-C

Boiling Point

202.8°Cat760mmHg

Density

1.088

Flash Point

76.4°C

SMILES

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Cl.ClCCN1CCOCC1

InChI

InChI=1S/C6H12ClNO.ClH/c7-1-2-8-3-5-9-6-4-8;/h1-6H2;1H

InChIKey

NBJHDLKSWUDGJG-UHFFFAOYSA-N

LogP

0.9792000000000001

Topological Polar Surface Area

12.47 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

73.5

Safety Information

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Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H312 Harmful in contact with skin
Acute toxicity, dermal

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

H317 May cause an allergic skin reaction
Sensitization, Skin

Hazard Class

Class 8 (6.1) Class 8 (6.1)

Sensitiveness

Hygroscopic

Synonyms & References

English

4-(2-Chloroethyl)morpholine hydrochloride
N-(2-Chloroethyl) morpholine HCl
2-(N-Morpholino)ethyl chloride hydrochloride
4-(2-chloroethyl)mopholine hydrochloride
4-(2-Chloroethyl)-Morpholine Hydrochloride
2-Morpholinoethyl Chloride Hydrochloride
N-(2-Chloroethyl)morpholine hydrochloride
Morpholine, 4-(2-chloroethyl)-, hydrochloride
2-Morpholinoethylchloride hydrochloride
4-(2-chloroethyl)morpholine HCl
Chloromorpholinoethane hydrochloride
(2-Chloroethyl)morpholine hydrochloride
4-(2-Chloroethyl)morpholinium chloride
Morpholine, 4-(2-chloroethyl)-, hydroc
2-Morpholinoethyl chloride hydrochloride
4-(2-chloroethyl)morpholine hydrochloride

MDL Number

MFCD00012797

Customs Code

2934999090

FAQ

What is 4-(2-Chloroethyl)morpholine hydrochloride (CAS: 3647-69-6)?

4-(2-Chloroethyl)morpholine hydrochloride (CAS: 3647-69-6) is a hydrochloride salt of 4-(2-chloroethyl)morpholine, with the chemical formula C6H14Cl2NO. It is a white crystalline solid, commonly used in organic synthesis. The compound exhibits solubility in water and is noted for its reactivity in pharmaceutical applications, particularly as an intermediate in drug development.

What are the main uses of 4-(2-Chloroethyl)morpholine hydrochloride (CAS: 3647-69-6)?

4-(2-Chloroethyl)morpholine hydrochloride (CAS: 3647-69-6) is primarily used in pharmaceuticals as an intermediate for synthesizing drugs like antipsychotics and antihistamines. It also serves in industrial chemical synthesis, research for developing new compounds, and as a chelating agent. Its versatility makes it a key component in various chemical processes and applications.

Is 4-(2-Chloroethyl)morpholine hydrochloride (CAS: 3647-69-6) safe?

4-(2-Chloroethyl)morpholine hydrochloride (CAS: 3647-69-6) requires careful handling due to potential skin and eye irritation. Safety standards classify it as a hazardous substance under GHS, necessitating protective measures like gloves and ventilation. While generally safe when used properly, it should be stored and handled according to OSHA guidelines to minimize exposure risks.

How should 4-(2-Chloroethyl)morpholine hydrochloride (CAS: 3647-69-6) be stored?

Store 4-(2-Chloroethyl)morpholine hydrochloride (CAS: 3647-69-6) in a sealed container, away from moisture, light, and heat. Maintain storage conditions at 25°C or below, in a cool, dry place. Ensure proper labeling and avoid exposure to air to preserve stability and prevent degradation over time.