(5Z,11alpha,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid

Basic Information

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CAS Number

363-24-6

Molecular Formula

C20H32O5

Molecular Weight

352.47 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

66°C

Boiling Point

530.1°C at 760 mmHg

Solubility

ethanol: 1 mg/mL

Refractive Index

1.6120 (estimate)

Specific Rotation

-85.5 º (c=1, C2H5OH)

SMILES

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CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1C/C=C\CCCC(=O)O

InChI

InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,19+/m0/s1

InChIKey

XEYBRNLFEZDVAW-ARSRFYASSA-N

LogP

3.251100000000002

Topological Polar Surface Area

94.83 Å²

Hydrogen Bond Donor/Acceptor

3 / 5

Complexity

469

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H360 May damage fertility or the unborn child
Reproductive toxicity

Synonyms & References

English

Prostaglandin E2
(5Z,11alpha,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
(5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprosta-5,13-dienoate
7-[3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl]-5-heptenoic acid
PGE2
Prosta-5,13-diene-1-oic acid, 11,15-dihydroxy-9-oxo-, (5Z,11a,13E15S)-
Dinoprostone
PGE2 (Prostaglandin E2)
Prostaglandin E2 Lipid Maps MS Standard
(Z)-7-((1R,2R,3R)-3-Hydroxy-2-((S,E)-3-hydroxyoct-1-en-1-yl)-5-oxocyclopentyl)hept-5-enoic acid
Cervidil
Cervidil(R)
Cerviprost
l-pge2
MCH (human,mouse,rat)
Prepidil
Propess
Prostenon
prostin
prostine2
(5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dienoic acid
(5Z,11a,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
Dinoprostone (prostaglandin E2)
Prostin E2
Minprositin E2
Minprostin E2
Dinoproston
(15S)-Prostaglandin E2
Prostarmon E
Dinoprostonum
l-Prostaglandin E2

MDL Number

MFCD00077861

FAQ

What is (5Z,11alpha,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid (CAS: 363-24-6)?

This compound, also known as (5Z,11alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid, is a prostaglandin derivative with the CAS number 363-24-6. It features a cyclopentane ring and is characterized by multiple double bonds and hydroxyl groups. The compound is known for its biological activity and is often studied in the context of inflammatory responses and lipid metabolism.

What are the main uses of (5Z,11alpha,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid (CAS: 363-24-6)?

This compound is primarily used in pharmaceutical research for its potential anti-inflammatory and analgesic properties. It also serves as a key intermediate in the synthesis of other bioactive molecules and is studied in the context of lipid signaling pathways. Its applications include drug development and biochemical studies.

Is (5Z,11alpha,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid (CAS: 363-24-6) safe?

The safety of this compound depends on its application and exposure level. It is generally considered safe in controlled research settings, but proper handling is required to avoid skin or eye contact. Safety data suggests it follows standard chemical handling protocols, and protective measures such as gloves and ventilation should be used when working with it.

How should (5Z,11alpha,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid (CAS: 363-24-6) be stored?

This compound should be stored in a cool, dry, and dark place, away from moisture and light. It is typically kept in a sealed container at a temperature below 25°C. Due to its chemical sensitivity, it is recommended to store it under inert gas conditions to maintain stability and prevent degradation.