9-(2-Deoxy-beta-D-erythro-pentofuranosyl)-9H-purin-2-amine | CAS No. 3616-24-8

9-(2-Deoxy-beta-D-erythro-pentofuranosyl)-9H-purin-2-amine

Basic Information

CAS Number

3616-24-8

Molecular Formula

C10H13N5O3

Molecular Weight

251.25 g/mol

AD

Basic Physical Properties

C1C(C(OC1N2C=NC3=CN=C(N=C32)N)CO)O

InChI

InChI=1S/C10H13N5O3/c11-10-12-2-5-9(14-10)15(4-13-5)8-1-6(17)7(3-16)18-8/h2,4,6-8,16-17H,1,3H2,(H2,11,12,14)/t6-,7+,8+/m0/s1

InChIKey

KGCFUCMAUQBXMT-XLPZGREQSA-N

LogP

-0.9508000000000005

Topological Polar Surface Area

119.30999999999999 Ų

Hydrogen Bond Donor/Acceptor

4 / 8

Complexity

307

Synonyms & References

English

  • 2-Aminopurine-9-beta-D-(2??-deoxy)riboside
  • (2R,3S,5R)-5-(2-amino-9H-purin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
  • 2-Aminopurine-2'-deoxyriboside
  • 2-AMINO-9-(beta-D-2-DEOXYRIBOFURANOSYL)PURINE
  • Fendizoic Acid Acetate
  • 2-Amino-9-(2'-deoxy-b-D-ribofuranosyl)purine
  • AKOS027379716
  • 3616-24-8
  • (2R,3S,5R)-5-(2-Amino-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol
  • (2R,3S,5R)-5-(2-AMINOPURIN-9-YL)-2-(HYDROXYMETHYL)OXOLAN-3-OL
  • SCHEMBL9151040
  • 9H-Purin-2-amine,9-(2-deoxy-b-D-erythro-pentofuranosyl)-
  • 2-AMINO-9-(2'-DEOXY-B-D-RIBOFURANOSYL)PURINE
  • 2-AMINO-9-(β-D-2-DEOXYRIBOFURANOSYL)PURINE
  • deoxyadenosine
  • purin-2-amine 2'-deoxyribonucleoside

MDL Number

MFCD01630951

Customs Code

2934999090

FAQ

What are the physical and chemical properties of 9-(2-Deoxy-beta-D-erythro-pentofuranosyl)-9H-purin-2-amine (CAS: 3616-24-8)?

9-(2-Deoxy-beta-D-erythro-pentofuranosyl)-9H-purin-2-amine (CAS: 3616-24-8) is a crystalline compound with a molecular weight of approximately 276.20 g/mol. It has a moderate solubility in water and is slightly soluble in organic solvents. The compound is known for its chemical stability and low reactivity under normal conditions. It is commonly used in pharmaceutical research due to its biological activity.

How is 9-(2-Deoxy-beta-D-erythro-pentofuranosyl)-9H-purin-2-amine (CAS: 3616-24-8) typically synthesized?

9-(2-Deoxy-beta-D-erythro-pentofuranosyl)-9H-purin-2-amine is typically synthesized through a condensation reaction of 9-aminopurine with 2-deoxy-β-D-erythro-pentofuranose. The reaction involves the use of a suitable base and is conducted under mild conditions. The yield is generally around 70-80%, and the product is purified by recrystallization from water or a suitable organic solvent.

What industries use 9-(2-Deoxy-beta-D-erythro-pentofuranosyl)-9H-purin-2-amine (CAS: 3616-24-8)?

9-(2-Deoxy-beta-D-erythro-pentofuranosyl)-9H-purin-2-amine (CAS: 3616-24-8) is primarily used in the pharmaceutical industry for the development of nucleoside analogs. It has applications in the production of antiviral and anticancer drugs. Additionally, it is of interest in academic and research settings for studying DNA and RNA synthesis and metabolism.

What precautions should be taken when handling 9-(2-Deoxy-beta-D-erythro-pentofuranosyl)-9H-purin-2-amine (CAS: 3616-24-8)?

When handling 9-(2-Deoxy-beta-D-erythro-pentofuranosyl)-9H-purin-2-amine (CAS: 3616-24-8), it is important to use proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The substance should be handled in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbent materials and the area should be washed with water. Always refer to a Safety Data Sheet (SDS) for detailed handling and disposal instructions.

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