Fluoroacetyl chloride

Basic Information

View in Editor

CAS Number

359-06-8

Molecular Formula

C2H2ClFO

Molecular Weight

96.49 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Specialty Chemicals UV Stabilizers

Electronic Chemicals Semiconductor Materials Etchants

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Water Treatment Chemicals Disinfectants Chlorine Compounds

Basic Physical Properties

Boiling Point

75-80 ºC (760 Torr)

Flash Point

-16.1±19.0 ºC,

Refractive Index

1.400 (589.3 nm 20 ºC)

SMILES

View in Editor

C(C(=O)Cl)F

InChI

InChI=1S/C2H2ClFO/c3-2(5)1-4/h1H2

InChIKey

ZBHDTYQJAQDBIH-UHFFFAOYSA-N

LogP

0.7213

Topological Polar Surface Area

17.07 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

44.9

Safety Information

View Safety Information

Hazard Class

Class 6.1(a) Class 6.1(a)

Synonyms & References

English

ZBHDTYQJAQDBIH-UHFFFAOYSA-N
FT-0600307
HSDB 6327
0CQX1ANG4H
Q1434179
MFCD00015738
Chlorid kyseliny fluoroctove [Czech]
2-fluoroacetyl chloride
fluoracetyl chloride
UNII-0CQX1ANG4H
Chlorid kyseliny fluoroctove
NS00041407
AKOS015853783
DTXSID4059885
TL 670
BRN 1739051
FLUOROACETYL CHLORIDE
359-06-8
EINECS 206-623-6
Acetyl chloride, 2-fluoro-
FLUOROACETYL CHLORIDE [HSDB]
Acetyl chloride, fluoro-
Fluoroacetyl chloride
Fluoro-acetic chloride
2-Fluoroacetyl chloride

MDL Number

MFCD00015738

Customs Code

2915900090

FAQ

What are the physical and chemical properties of Fluoroacetyl chloride (CAS: 359-06-8)?

Fluoroacetyl chloride is a colorless or slightly yellow liquid with a molecular weight of 122.54 g/mol. It has a pKa of around 3.5 and is highly soluble in water and organic solvents. It is a strong acid and a potent electrophile, reacting readily with nucleophiles. Proper storage in a cool, dark place away from moisture and heat is necessary due to its reactivity.

How is Fluoroacetyl chloride (CAS: 359-06-8) typically synthesized?

Fluoroacetyl chloride is often synthesized via the reaction of acetyl chloride with hydrogen fluoride, followed by dehydration to remove water. Typical yield is around 85-90%, and the process requires careful control of temperature and pressure to ensure high selectivity and yield.

What industries use Fluoroacetyl chloride (CAS: 359-06-8)?

Fluoroacetyl chloride finds application in pharmaceuticals for the synthesis of certain drugs, polymers for functionalization, and sensors for detection of various analytes. It is also used in semiconductor manufacturing for etching and surface modification.

What precautions should be taken when handling Fluoroacetyl chloride (CAS: 359-06-8)?

Handling Fluoroacetyl chloride requires strict safety measures. Always wear personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or fume hood to avoid inhalation. Spills should be handled with appropriate absorbents and disposed of according to the SDS. Keep away from heat and moisture sources. Always consult the Safety Data Sheet (SDS) for detailed handling instructions.