6-Chloro-3-pyridazinecarbonitrile

Basic Information

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CAS Number

35857-89-7

Molecular Formula

C5H2ClN3

Molecular Weight

139.54 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Nitriles

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

335.1°C at 760 mmHg

Flash Point

156.5℃

SMILES

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C1=CC(=NN=C1C#N)Cl

InChI

InChI=1S/C5H2ClN3/c6-5-2-1-4(3-7)8-9-5/h1-2H

InChIKey

YMUOLGNUZURDEW-UHFFFAOYSA-N

LogP

1.00168

Complexity

138

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

35857-89-7
BCP33737
3-PYRIDAZINECARBONITRILE, 6-CHLORO-
Z1198233597
F2147-0172
EN300-80756
SCHEMBL732152
AM20090568
6-chloro-pyridazine-3-carbonitrile
MFCD09835352
FT-0650403
3-CHLORO-6-CYANOPYRIDAZINE
YMUOLGNUZURDEW-UHFFFAOYSA-N
3-Chloro-6-cyanopyridazine;3-Pyridazinecarbonitrile, 6-chloro-
AKOS005206933
6-chloropyridazine-3-carbonitrile
SY009543
GS-4273
J-518645
6-Chloro-3-pyridazinecarbonitrile
A823005
DTXSID00538939
CS-W005102
6-chloranylpyridazine-3-carbonitrile
PB28049
6-Chloropyridazine-3-carbonitrile
3-chloro-6-cyanopyridazine
3-Pyridazinecarbonitrile, 6-chloro-
3-cyano-6-chloropyridazine
3-PYRIDAZINECARBONITRILE,6-CHLORO
6-Chlor-pyridazin-3-carbonitril

MDL Number

MFCD09835352

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 6-Chloro-3-pyridazinecarbonitrile (CAS: 35857-89-7)?

6-Chloro-3-pyridazinecarbonitrile is a white crystalline solid with a molecular weight of approximately 165.01 g/mol. It has a low solubility in water but is more soluble in organic solvents like acetone and ethanol. Chemically, it is relatively stable under normal conditions but can undergo hydrolysis in the presence of moisture or acid. It is a potent electrophile and can react with nucleophiles to form various adducts.

How is 6-Chloro-3-pyridazinecarbonitrile (CAS: 35857-89-7) typically synthesized?

6-Chloro-3-pyridazinecarbonitrile is usually synthesized via the reaction of chloroacetonitrile with 3-pyridazinecarboxaldehyde. The reaction is typically catalyzed by a strong acid like concentrated sulfuric acid. The yield is around 85-90%, with good selectivity for the desired product. The reaction is exothermic and must be carefully monitored to prevent side reactions.

What industries use 6-Chloro-3-pyridazinecarbonitrile (CAS: 35857-89-7)?

6-Chloro-3-pyridazinecarbonitrile finds application in the pharmaceutical industry, where it is used as an intermediate in the synthesis of certain drugs. It is also utilized in the polymer industry for the development of advanced polymers with specific properties. Additionally, it is employed in the electronics industry for the production of semiconductors and sensors due to its unique electronic properties.

What precautions should be taken when handling 6-Chloro-3-pyridazinecarbonitrile (CAS: 35857-89-7)?

When handling 6-Chloro-3-pyridazinecarbonitrile, it is crucial to wear appropriate personal protective equipment, including gloves, goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood due to its potential to release toxic fumes. Spills should be cleaned up immediately with appropriate containment measures. Always consult the Safety Data Sheet (SDS) for detailed handling and storage instructions.