N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanine

Basic Information

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CAS Number

35661-39-3

Molecular Formula

C18H17NO4

Molecular Weight

311.34 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

147-153 °C

Boiling Point

483.6°C at 760 mmHg

Water Solubility

Soluble in water.

Flash Point

282.9 °C

Refractive Index

-18.5 ° (C=1, DMF)

Specific Rotation

-19 º (c=1,DMF)

SMILES

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CC(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

InChI

InChI=1S/C18H17NO4/c1-11(17(20)21)19-18(22)23-10-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16/h2-9,11,16H,10H2,1H3,(H,19,22)(H,20,21)/t11-/m0/s1

InChIKey

QWXZOFZKSQXPDC-NSHDSACASA-N

LogP

2.9982000000000006

Topological Polar Surface Area

75.63 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

430

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

InChI=1/C18H17NO4/c1-11(17(20)21)19-18(22)23-10-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16/h2-9,11,16H,10H2,1H3,(H,19,22)(H,20,21)/t11-/m0/s1
(s)-2-(9h-fluoren-9-ylmethoxycarbonylamino)-propionic acid
BP-23514
AC-8579
CS-W009920
AMY365
N-(9-Fluorenylmethoxycarbonyl)-L-alanine
Fmoc-Ala
DTXSID001245823
AM81480
HY-W009204
EN300-74032
M03347
Fmoc-Ala-OH, 95%
L-Alanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
Fmoc-L-alanine
FMOC-L-ALA
AKOS005175159
J-300006
FMOC-ALANINE
DS-13759
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoate;N-Fmoc-L-alanine
9-Fmoc-L-alanine
(-)-L-Alanine, N-FMOC protected
QWXZOFZKSQXPDC-NSHDSACASA-
Na-9-Fluorenylmethoxycarbonyl-L-alanine
N-Fmoc-L-alanine
D72711
SCHEMBL119044
FD21028
AKOS015924056

MDL Number

MFCD00037139

FAQ

What is N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanine (CAS: 35661-39-3)?

N-[(9H-Fluoren-9-ylmeth oxy)carbonyl]-L-alanine is a chemical compound with the CAS number 35661-39-3. It is an amino acid derivative commonly used in organic synthesis. The compound features a fluorenylmethoxy carbonyl (Fmoc) protecting group attached to the L-alanine molecule, making it valuable in peptide chemistry and bioconjugation applications.

What are the main uses of N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanine (CAS: 35661-39-3)?

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanine is primarily used in pharmaceutical research and synthesis as a protecting group for amino acids. It is also employed in the production of peptides, drug development, and bioconjugation processes. Its applications extend to organic chemistry and molecular biology research due to its stability and reactivity in controlled environments.

Is N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanine (CAS: 35661-39-3) safe?

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alan ine is generally considered safe when handled properly. However, as a chemical compound, it should be treated with standard laboratory precautions. Users should wear appropriate personal protective equipment (PPE) and follow safety guidelines to avoid skin contact or inhalation. It is not classified as toxic under normal usage conditions.

How should N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanine (CAS: 35661-39-3) be stored?

N-[(9H-Fluoren-9-ylmet hoxy)carbonyl]-L-alanine should be stored in a cool, dry, and dark place to maintain its stability. It is typically kept in a sealed container at temperatures below 25°C and away from moisture and light. Proper storage helps preserve its chemical integrity and prolongs shelf life in laboratory and industrial settings.