N-[(4-Chlorophenyl)carbamoyl]-2,6-difluorobenzamide

Basic Information

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CAS Number

35367-38-5

Molecular Formula

C14H9ClF2N2O2

Molecular Weight

310.69 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

230-232 ºC

Water Solubility

0.008 g/100 mL

Solubility

Soluble in methanol, DMSO, acetone (6.5 mg/ml at 20 °C), and ethanol. Insoluble in water.

Refractive Index

1.5221

SMILES

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O=C(NC(=O)c1c(F)cccc1F)Nc1ccc(cc1)Cl

InChI

InChI=1S/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21)

InChIKey

QQQYTWIFVNKMRW-UHFFFAOYSA-N

LogP

3.5801000000000016

Topological Polar Surface Area

58.2 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

379

Safety Information

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GHS Hazard Pictograms

H312

H410

Hazard Statement

H312 Harmful in contact with skin
Acute toxicity, dermal

H410 Very toxic to aquatic life with long lasting effects
Hazardous to the aquatic environment, long-term hazard

Hazard Class

Class 9 Class 9

Sensitiveness

对光线敏感

Toxicity

LD50 in mice, rats (formulation with 50% kaolin) (g/kg): 4.64, >10 orally (Mulder, Gijswijt)

Synonyms & References

English

Diflubenzuron
3-(2,6-Difluorobenzoyl)-1-(4-chlorophenyl)urea
1-(4-chlorophenyl)-3-(2,6-difluorobenzoyl)urea
difluron
Dimilin
DU 112307
Largon
Micromite
N-(((4-chlorophenyl)amino)carbonyl)-2,6-difluorobenzamide
PDD 6040-I
Diflubenzuron solution
Phenylurea Pesticide Mixture
Phenylurea Primary Dilution Standard
astonex
DIMILAN
N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide
N-[[(4-chlorophenyl)amino]carbonyl]-2,6-difluorobenzamide
oms1804
PH60-40
th6040
1-(4-Chlorophenyl)-3-(2,6-difluorobenzoyl)urea
N-((4-chlorophenyl)carbamoyl)-2,6-difluorobenzamide

MDL Number

MFCD00055343

FAQ

What is N-[(4-Chlorophenyl)carbamoyl]-2,6-difluorobenzamide (CAS: 35367-38-5)?

N-[(4-Chlorophenyl)carbamoyl]-2,6-difluorobenzamide (CAS: 35367-38-5) is an organic compound with the chemical formula C14H9ClF2NO3. It features a benzamide core substituted with a 4-chlorophenyl group and fluorine atoms at the 2 and 6 positions. This compound exhibits moderate solubility in polar solvents and is commonly used as a pharmaceutical intermediate due to its functional groups and reactivity.

What are the main uses of N-[(4-Chlorophenyl)carbamoyl]-2,6-difluorobenzamide (CAS: 35367-38-5)?

N-[(4-Chlorophenyl)carbamoyl]-2,6-difluorobenzamide (CAS: 35367-38-5) is primarily utilized in pharmaceutical research for the development of drug molecules targeting metabolic disorders. Its applications also extend to industrial chemistry as a component in pesticide formulations and polymer synthesis. Additionally, it serves as a key intermediate in the production of agrochemicals and organic materials with tailored properties.

Is N-[(4-Chlorophenyl)carbamoyl]-2,6-difluorobenzamide (CAS: 35367-38-5) safe?

N-[(4-Chlorophenyl)carbamoyl]-2,6-difluorobenzamide (CAS: 35367-38-5) is generally considered safe when handled properly. However, it may pose health risks if exposed to high concentrations, so appropriate safety measures are essential. Toxicity data suggest potential irritant effects, and users should wear personal protective equipment (PPE) like gloves and goggles. Always follow safety standards for chemical handling in laboratories or industrial settings.

How should N-[(4-Chlorophenyl)carbamoyl]-2,6-difluorobenzamide (CAS: 35367-38-5) be stored?

N-[(4-Chlorophenyl)carbamoyl]-2,6-difluorobenzamide (CAS: 35367-38-5) should be stored in a cool, dry place (ideally below 25°C), protected from light. Keep it in a sealed, airtight container made of glass or stainless steel to maintain stability. Avoid exposure to moisture and incompatible substances to prevent degradation or hazardous reactions.