Delafloxacin Meglumine

Basic Information

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CAS Number

352458-37-8

Molecular Formula

C25H29ClF3N5O9

Molecular Weight

635.98 g/mol

Basic Physical Properties

SMILES

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CNCC(C(C(C(CO)O)O)O)O.C1C(CN1C2=C(C=C3C(=C2Cl)N(C=C(C3=O)C(=O)O)C4=C(C=C(C(=N4)N)F)F)F)O

InChI

InChI=1S/C18H12ClF3N4O4.C7H17NO5/c19-12-13-7(1-9(20)14(12)25-3-6(27)4-25)15(28)8(18(29)30)5-26(13)17-11(22)2-10(21)16(23)24-17;1-8-2-4(10)6(12)7(13)5(11)3-9/h1-2,5-6,27H,3-4H2,(H2,23,24)(H,29,30);4-13H,2-3H2,1H3/t;4-,5+,6+,7+/m.0/s1

InChIKey

AHJGUEMIZPMAMR-WZTVWXICSA-N

LogP

-1.4405999999999974

Topological Polar Surface Area

234.85999999999999 Å²

Hydrogen Bond Donor/Acceptor

10 / 14

Complexity

889

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

ABT-492 Meglumine
(2R,3R,4R,5S)-2,3,4,5-Tetrahydroxy-6-(methylamino)hexyl 1-(6-amino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxo-1,4-dihydroquin
1-(6-amino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxoquinoline-3-c
1-(6-amino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxoquinoline-3-carboxylic acid,(2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol
Delafloxacin meglumine
1-(6-amino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxoquinoline-3-carboxylic acid;(2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol
RX-3341 meglumine
Delafloxacin (meglumine)
N7V53U4U4T
DTXSID90188740
D70784
Delafloxacin meglumine [USAN]
CS-1479
UNII-N7V53U4U4T
EX-A3992
D09331
D-Glucitol, 1-deoxy-1-(methylamino)-, 1-(6-amino-3,5-difluoro-2-pyridinyl)-8-chloro-6-fluoro-1,4-dihydro-7-(3-hydroxy-1-azetidinyl)-4-oxo-3-quinolinecarboxylate (salt)
DELAFLOXACIN MEGLUMINE [MI]
ABT-492;RX-3341;WQ-3034;Baxdela
(2R,3R,4R,5S)-6-(Methylamino)hexane-1,2,3,4,5-pentaol 1-(6-amino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylate
ABT-492 meglumine
BS-16614
s4488
Baxdela (TN)
WQ-3034 AND ABT-492
AC-36496
CHEMBL2105638
1-Deoxy-1-(methylamino)-D-glucitol 1-(6-amino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylate (salt)
Delafloxacin meglumine (ABT492 meglumine; RX-3341 meglumine; WQ-3034 meglumine)
C25H29ClF3N5O9
DELAFLOXACIN MEGLUMINE [WHO-DD]

MDL Number

MFCD26142921

FAQ

What regulatory guidelines apply to Delafloxacin Meglumine (CAS: 352458-37-8)?

Regulatory guidelines for Delafloxacin Meglumine (CAS: 352458-37-8) include the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), Registration, Evaluation, Authorization and Restriction of Chemicals (REACH) regulations in the EU, and requirements from the Food and Drug Administration (FDA) and Environmental Protection Agency (EPA) in the US. Compliance with local regulations is also essential.

Are there alternatives to Delafloxacin Meglumine (CAS: 352458-37-8) in synthesis?

There are several alternatives to Delafloxacin Meglumine (CAS: 352458-37-8) in synthesis, including other fluoroquinolone antibiotics. Common alternatives include moxifloxacin and levofloxacin, which share similar properties and can serve as effective substitutes in certain applications.

What is the market or research trend for Delafloxacin Meglumine (CAS: 352458-37-8)?

The market for Delafloxacin Meglumine (CAS: 352458-37-8) is steadily growing due to its broad-spectrum antibacterial properties. Research trends focus on understanding its pharmacokinetics, efficacy in various infections, and potential side effects. Additionally, there is an increasing interest in its use in treating respiratory and urinary tract infections.

How should waste containing Delafloxacin Meglumine (CAS: 352458-37-8) be handled?

Waste containing Delafloxacin Meglumine (CAS: 352458-37-8) should be collected in appropriate containers and disposed of through professional waste disposal services. Incineration is a common method for waste disposal, and proper environmental protection measures, such as limiting exposure to air and water, should be followed to prevent pollution. Compliance with local and national waste disposal regulations is essential.