2-Methyl-5-pyrimidinol

Basic Information

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CAS Number

35231-56-2

Molecular Formula

C5H6N2O

Molecular Weight

110.12 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

175-179 ºC

Boiling Point

208 ºC

Flash Point

80 ºC

Refractive Index

1.556

SMILES

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CC1=NC=C(C=N1)O

InChI

InChI=1S/C5H6N2O/c1-4-6-2-5(8)3-7-4/h2-3,8H,1H3

InChIKey

OHFVPBGSKPYIED-UHFFFAOYSA-N

LogP

0.4906199999999999

Topological Polar Surface Area

46.010000000000005 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

68.8

Synonyms & References

English

AC-22327
2-methyl-5hydroxypyrimidine
J-510096
2-Methylpyrimidin-5-ol pound>>5-Pyrimidinol, 2-methyl-
CS-W005972
35231-56-2
DTXSID60336731
FT-0603733
BCP30393
A6187
5-Pyrimidinol, 2-methyl-
2-METHYL-5-HYDROXYPYRIMIDINE
DS-11040
SCHEMBL754165
2-Methyl-pyrimidin-5-ol
AB54467
2-Methyl-5-pyrimidinol
SY045130
2-Methyl-5-pyrimidinol #
AKOS006282504
2-Methylpyrimidin-5-ol
2-methylpyrimidine-5-ol
AMY10280
MFCD09879706
5-Hydroxy-2-methylpyrimidine
2-Methyl-5-hydroxypyrimidine
2-Methyl-5-pyrimidin
OHFVPBGSKPYIED-UHFFFAOYSA-N
PubChem21855
KSC497M5D
CH0061

MDL Number

MFCD09879706

Customs Code

2933599090

FAQ

What are the physical and chemical properties of 2-Methyl-5-pyrimidinol (CAS: 35231-56-2)?

2-Methyl-5-pyrimidinol (CAS: 35231-56-2) is a crystalline solid with a molecular weight of approximately 98.13 g/mol. It has a solubility of around 1.4 g/100 mL in water. This compound is reactive towards bases and can undergo nucleophilic substitution reactions. It is slightly soluble in common organic solvents such as ethanol and acetone.

How is 2-Methyl-5-pyrimidinol (CAS: 35231-56-2) typically synthesized?

2-Methyl-5-pyrimidinol (CAS: 35231-56-2) is typically synthesized through the reduction of 2-methyl-5-pyrimidone using a reducing agent like sodium borohydride in an aqueous solution. The reaction is conducted under mild conditions to achieve a high yield, often around 85-90%. The use of a suitable catalyst or solvent can enhance the selectivity and efficiency of the process.

What industries use 2-Methyl-5-pyrimidinol (CAS: 35231-56-2)?

2-Methyl-5-pyrimidinol (CAS: 35231-56-2) finds application in the pharmaceutical industry for the synthesis of certain drugs. It is also used in the chemical industry for the production of polymers and in sensors for its reactivity. Additionally, it can be used in the semiconductor industry for specific applications that require its unique physicochemical properties.

What precautions should be taken when handling 2-Methyl-5-pyrimidinol (CAS: 35231-56-2)?

When handling 2-Methyl-5-pyrimidinol (CAS: 35231-56-2), it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. This compound should be handled in a well-ventilated area or a fume hood due to its reactivity. In case of a spill, it should be cleaned up with care to avoid skin contact or inhalation. Always refer to the Safety Data Sheet (SDS) for detailed safety information and proper handling procedures.