1-Ethyl-4-piperidinol

Basic Information

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CAS Number

3518-83-0

Molecular Formula

C7H15NO

Molecular Weight

129.2 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

114-116 ºC (0.005 Torr)

Flash Point

95.6±0.0 ºC,

Refractive Index

1.4800 (589.3 nm 20 ºC)

SMILES

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CCN1CCC(CC1)O

InChI

InChI=1S/C7H15NO/c1-2-8-5-3-7(9)4-6-8/h7,9H,2-6H2,1H3

InChIKey

AHOJTPZHHMJMCW-UHFFFAOYSA-N

LogP

0.4629999999999999

Topological Polar Surface Area

23.47 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

Synonyms & References

English

NS00029799
4-Piperidinol, 1-ethyl-
1-Ethyl-4-piperidinol
N-ethyl-4-hydroxy piperidine
J-019982
CHEMBL4526324
3518-83-0
SY033662
Z197264618
DTXSID00188670
EINECS 222-528-2
1-ethyl-piperidin-4-ol
AS-17355
CS-M1296
1-Ethyl-4-piperidinol #
1-Ethyl-4-hydroxypiperidine
4-hydroxy-N-ethylpiperidine
4-hydroxy-1-ethylpiperidine
AM20090554
EN300-45452
MB00190
A822634
AKOS000249636
SCHEMBL69424
M2F8HJ4QKP
J-523562
InChI=1/C7H15NO/c1-2-8-5-3-7(9)4-6-8/h7,9H,2-6H2,1H
FT-0634887
MFCD00006509
UNII-M2F8HJ4QKP
1-Ethylpiperidin-4-ol

MDL Number

MFCD00006509

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 1-Ethyl-4-piperidinol (CAS: 3518-83-0)?

1-Ethyl-4-piperidinol (CAS: 3518-83-0) is a colorless, viscous liquid with a molecular weight of approximately 129.22 g/mol. It is slightly soluble in water but miscible with organic solvents. This compound has a pKa of about 11.0 and is moderately reactive towards nucleophiles. It can form stable salts with acids.

How is 1-Ethyl-4-piperidinol (CAS: 3518-83-0) typically synthesized?

1-Ethyl-4-piperidinol is typically synthesized via alkylation of 4-piperidone with ethyl iodide in the presence of a base such as potassium tert-butoxide. The reaction is carried out in anhydrous conditions to ensure optimal yield and selectivity.

What industries use 1-Ethyl-4-piperidinol (CAS: 3518-83-0)?

1-Ethyl-4-piperidinol is used in the pharmaceutical industry for the synthesis of certain drugs, in the polymer industry for modifying polymer properties, and in the electronic industry for its use in sensors and as a semiconductor precursor.

What precautions should be taken when handling 1-Ethyl-4-piperidinol (CAS: 3518-83-0)?

When handling 1-Ethyl-4-piperidinol (CAS: 3518-83-0), safety goggles and gloves should be worn. It should be stored in a cool, dry place away from heat and sources of ignition. In case of spill, use appropriate PPE and refer to the Safety Data Sheet (SDS) for detailed spill management procedures.