6-Chloro-pyrimidine-2,4-diamine 3-Oxide

Basic Information

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CAS Number

35139-67-4

Molecular Formula

C4H5ClN4O

Molecular Weight

160.56 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

185 ºC (dec.)

SMILES

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C1=C(N(C(=N)N=C1Cl)O)N

InChI

InChI=1S/C4H5ClN4O/c5-2-1-3(6)9(10)4(7)8-2/h1,7,10H,6H2

InChIKey

DOYINGSIUJRVKA-UHFFFAOYSA-N

LogP

1.49030

Complexity

233

Synonyms & References

English

SCHEMBL2292431
6-?Chloro-?2,?3-?dihydro-?3-?hydroxy-?2-?imino-4-?pyrimidinamine
34960-71-9
Minoxidil Imp. A (EP): 6-Chloropyrimidine-2,4-diamine 3-Oxide
Minoxidil Impurity A
2,6-Diamino-4-chloropyrimidine 1-oxide; Minoxidil EP Impurity A pound>>6-Chloro-pyrimidine-2,4-diamine 3-Oxide
AMY25267
C4H5ClN4O
BCP31046
2,6-Diamino-4-chloropyrimidine 1-oxide, 98%
NSC-137211
DTXSID801204863
6-Amino-4-chloro-2-iminopyrimidin-1(2H)-ol
6-Chloro-2,3-dihydro-3-hydroxy-2-imino-4-pyrimidinamine
2,6-Diamino-4-chloropyrimidine-1-oxide
2,6-Diamino-4-chloropyrimidine 1-oxide
SCHEMBL9621590
DOYINGSIUJRVKA-UHFFFAOYSA-N
2,4-diamino-6-chloropyrimidine 3-oxide
N10804
6-chloro-3-hydroxy-2-iminopyrimidin-4-amine
6-amino-4-chloro-1,2-dihydro-2-imino-1-pyrimidinol
Minoxidil EP Impurity A
35139-67-4
6-chloropyrimidine-2,4-diamine 3-oxide
Minoxidil impurity A [EP impurity]
AKOS005458824
2,4-diamino-6-chloropyrimidine-3-oxide
2,4-diamino-6-chloro-pyrimidine-3-oxide
FT-0661669
6-amino-4-chloro-1,2-dihydro-1-hydroxy-2-imino pyrimidine

MDL Number

MFCD00134274

Customs Code

2933599090

FAQ

What are the physical and chemical properties of 6-Chloro-pyrimidine-2,4-diamine 3-Oxide (CAS: 35139-67-4)?

6-Chloro-pyrimidine-2,4-diamine 3-Oxide is a white crystalline solid with a molecular weight of approximately 213.02 g/mol. It is slightly soluble in water and organic solvents. The compound exhibits basic properties, reacting with acids to form salts. It is stable under normal conditions but decomposes at high temperatures, releasing chlorine gas.

How is 6-Chloro-pyrimidine-2,4-diamine 3-Oxide (CAS: 35139-67-4) typically synthesized?

6-Chloro-pyrimidine-2,4-diamine 3-Oxide is synthesized through the reaction of 6-chloropyrimidine-2,4-diamine with an oxidizing agent, such as potassium permanganate, in an aqueous medium. The process involves the oxidation of the primary amine, resulting in the formation of an imine intermediate and subsequent cyclization to form the target compound.

What industries use 6-Chloro-pyrimidine-2,4-diamine 3-Oxide (CAS: 35139-67-4)?

6-Chloro-pyrimidine-2,4-diamine 3-Oxide finds applications in various industries. It is used as a precursor in the pharmaceutical industry for the synthesis of antiviral and anticancer drugs. Additionally, it plays a role in the development of sensors and semiconductors due to its chemical properties.

What precautions should be taken when handling 6-Chloro-pyrimidine-2,4-diamine 3-Oxide (CAS: 35139-67-4)?

Proper handling procedures are essential when working with 6-Chloro-pyrimidine-2,4-diamine 3-Oxide. Always wear appropriate personal protective equipment (PPE), including gloves, goggles, and lab coats. Conduct reactions in a well-ventilated fume hood to minimize exposure to chlorine gas. In the event of a spill, neutralize the compound with an appropriate base and dispose of according to local hazardous waste regulations. Refer to the Safety Data Sheet (SDS) for detailed handling and safety information.