6-Chloro-pyrimidine-2,4-diamine 3-Oxide(CAS: 35139-67-4)

6-Chloro-pyrimidine-2,4-diamine 3-Oxide is a white crystalline solid with a molecular weight of approximately 213.02 g/mol. It is slightly soluble in water and organic solvents. The compound exhibits basic properties, reacting with acids to form salts. It is stable under normal conditions but decomposes at high temperatures, releasing chlorine gas.

6-Chloro-pyrimidine-2,4-diamine 3-Oxide is synthesized through the reaction of 6-chloropyrimidine-2,4-diamine with an oxidizing agent, such as potassium permanganate, in an aqueous medium. The process involves the oxidation of the primary amine, resulting in the formation of an imine intermediate and subsequent cyclization to form the target compound.

6-Chloro-pyrimidine-2,4-diamine 3-Oxide finds applications in various industries. It is used as a precursor in the pharmaceutical industry for the synthesis of antiviral and anticancer drugs. Additionally, it plays a role in the development of sensors and semiconductors due to its chemical properties.

Proper handling procedures are essential when working with 6-Chloro-pyrimidine-2,4-diamine 3-Oxide. Always wear appropriate personal protective equipment (PPE), including gloves, goggles, and lab coats. Conduct reactions in a well-ventilated fume hood to minimize exposure to chlorine gas. In the event of a spill, neutralize the compound with an appropriate base and dispose of according to local hazardous waste regulations. Refer to the Safety Data Sheet (SDS) for detailed handling and safety information.